Abstract
OBIGrid provides high-throughput GRIDBLAST services (OBIGbs) for researchers who need to deal with many BLAST query sequences at one time by exploiting both distributed processing and parallel processing. A new application-oriented grid framework has been introduced to split a BLAST query into independent sub-queries and to execute the sub-queries on remote personal computers and PC clusters connected by a virtual private network (VPN) over the Internet. The framework consists of five functional units: query splitter, job dispatcher, task manager, result collector and result formatter. They enable us to develop a cooperative GRIDBLAST system between a server and heterogeneous remote worker nodes: which consist of various computer architectures, different BLAST implementations and different Job schedulers operated by local resource management policy. The OBIGbs can execute 29,941 PSI-BLAST query sequences in 8.31 hours when using 230 CPUs in total and can return a 1.37 Giga byte result file.
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Konishi, F., Konagaya, A. (2005). The Architectural Design of High-Throughput BLAST Services on OBIGrid. In: Konagaya, A., Satou, K. (eds) Grid Computing in Life Science. LSGRID 2004. Lecture Notes in Computer Science(), vol 3370. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-32251-1_4
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DOI: https://doi.org/10.1007/978-3-540-32251-1_4
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-25208-5
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