Abstract
We describe a surgical planning environment that permits the determination or refinement of the location of a therapeutic neurosurgical intervention using information derived from an electrophysiological database. Such intraoperative stimulation-response and microelectrode recording data are generated from subcortical exploration performed as part of neurosurgical interventions at multiple centres. We have quantified and nonlinearly registered these intraoperative data, acquired from a large population of patients, to a reference brain imaging volume to create an electrophysiological database. This database can then be nonlinearly registered to future patient imaging volumes, enabling the delineation of surgical targets, cell types, and functional and anatomical borders prior to surgery. The user interface to our system allows the population-acquired physiology information to be accessed in a fully searchable format within a patient imaging volume. This system may be employed in both preoperative planning and intraoperative guidance of stereotactic neurosurgical procedures. We demonstrate preliminary results illustrating the use of this database approach to predict the optimum surgical site for creating thalamic lesions in the surgical treatment of Parkinson’s disease.
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Favre, J., Taha, J.M., Nguyen, T.T., Gildenberg, P.L., Burchiel, K.J.: Pallidotomy: A survey of current practice in North America. Neurosurgery 39, 883–892 (1996)
St-Jean, P., Sadikot, A.F., Collins, D.L., Clonda, D., Kasrai, R., Evans, A.C., Peters, T.M.: Automated atlas integration and interactive 3-dimensional visualization tools for planning and guidance in functional neurosurgery. IEEE Trans. Medical Imaging 17(5), 672–680 (1998)
Yeo, T.T., Nowinsky, W.L.: Functional neurosurgery aided by use of an electronic brain atlas. Acta Neurochir. [suppl.] 68, 93–99 (1997)
Penfield, W., Rasmussen, T.: The Cerebral Cortex of Man: A Clinical Study of Localization of Function. Macmillan, New York (1950)
Thompson, C.J., Hardy, T.L., Bertrand, G.: A system for anatomical and functional mapping of the human thalamus. Comput. Biomed. Res. 10, 9–24 (1977)
Tasker, R.R., Hawrylyshyn, P., Organ, W.: Computerized graphic display of physiological data collected during human stereotactic surgery. Appl. Neurophysiol. 41, 193–187 (1978)
Yoshida, M., Okada, K., Nagase, A., Kuga, S., Watanabe, M., Kuramoto, S.: Neurophysiological atlas of the human thalamus and adjacent structures. Appl. Neurophysiol. 45, 406–409 (1982)
Hardy, T.L.: A method for MRI and CT mapping of diencephalic somatotopography. Stereotact. Funct. Neurosurg. 52, 242–249 (1989)
Tasker, R.R., Hawrylyshyn, P., Organ, W.: Computerized graphic display of physiological data collected during human stereotactic surgery. Appl. Neurophysiol. 41, 193–187 (1978)
Collins, D.L., Peters, T.M., Evans, A.C.: An automated 3D non-linear image deformation procedure for determination of gross morphometric variability in the human brain. In: Robb, R.A. (ed.) SPIE. Proceedings of the Third Conference on Visualization in Biomedical Computing, Seattle WA, vol. 2359, pp. 180–190 (1994)
Holmes, C.J., Hoge, R., Collins, D.L., Woods, R., Toga, A.W., Evans, A.C.: Enhancement of MR images using registration for signal averaging. JCAT 22, 324–333 (1998)
Hardy, T.L., Bertrand, G., Thompson, C.J.: Organization and topography of sensory responses in the internal capsule and nucleus Ventralis caudalis found during stereotactic surgery. Appl. Neurophysiol. 42, 235–351 (1979)
Tasker, R.R., Organ, W., Hawrylyshyn, P.: The Thalamus and Midbrain of Man. Charles C. Thomas Publisher, Springfield (1982)
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Finnis, K.W., Starreveld, Y.P., Parrent, A.G., Peters, T.M. (2000). A 3-Dimensional Database of Deep Brain Functional Anatomy, and Its Application to Image-Guided Neurosurgery. In: Delp, S.L., DiGoia, A.M., Jaramaz, B. (eds) Medical Image Computing and Computer-Assisted Intervention – MICCAI 2000. MICCAI 2000. Lecture Notes in Computer Science, vol 1935. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-40899-4_1
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DOI: https://doi.org/10.1007/978-3-540-40899-4_1
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