Abstract
A method is presented for the estimation of dense breast tissue volume from full-field digital mammograms. The digital signal from the image is determined by using a physical signal propagation model that considers the incident x-ray spectrum and detector efficiency, assuming that the breast is composed of only adipose and fibroglandular tissue. The effect of an error in the breast thickness on the volumetric breast density (VBD) was studied using the model by replacing a curved thickness profile, as measured by optical photogrammetry on a compressed breast, by a constant thickness. It was found that a constant thickness approximation within 2% of the mean of the curved thickness is sufficient to keep the error within 5 %VBD units for breasts of 10%, 25%, 50% and 75% density. Relying on the thickness readout of mammography units typically induces large errors in the VBD estimation.
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References
Wolfe, J.N.: Breast patterns as an index of risk for developing breast cancer. AJR Am. J. Roentgenol. 126, 1130–1137 (1976)
Boyd, N.F., Guo, H., Martin, L.J., Sun, L., Stone, J., Fishell, E., Jong, R.A., Hislop, G., Chiarelli, A., Minkin, S., Yaffe, M.J.: Mammographic Density and the Risk and Detection of Breast Cancer. N. Engl. J. Med. 356, 227–236 (2007)
Byng, J.W., Boyd, N.F., Fishell, E., Jong, R.A., Yaffe, M.J.: The quantitative analysis of mammographic densities. Phys. Med. Biol. 39, 1629–1638 (1994)
Saha, P.K., Udupa, J.K., Conant, E.F., Chakraborty, D.P., Sullivan, D.: Breast tissue density quantification via digitized mammograms. IEEE Trans. Med. Imag. 20(8), 792–803 (2001)
Highnam, R., Brady, M., Shepstone, B.: A representation for mammographic image processing. Med. Image Anal. 1, 1–18 (1996)
Pawluczyk, O., Augustine, B.J., Yaffe, M.J., Rico, D., Yang, J., Mawdsley, G.: A volumetric method for estimation of breast density on digitized screen-film mammograms. Med. Phys. 30(3), 352–364 (2003)
van Engeland, S., Snoeren, P.R., Huisman, H., Boetes, C., Karssemeijer, N.: Volumetric Breast Density Estimation From Full-Field Digital Mammograms. IEEE Tans. Med. Im. 25(3), 273–282 (2006)
Blot, L., Zwiggelaar, R.: A volumetric approach to glandularity estimation in mammography: a feasibility study. Phys. Med. Biol. 50, 695–708 (2005)
Yang, J., Rico, D., Augustine, B., Mawdsley, G.E., Yaffe, M.J.: An optical method for measuring compressed breast thickness. In: 6th International workshop in digital mammography proceeding, pp. 569–573. Springer, Berlin (2002)
Tyson, A.H., Mawdsley, G.E., Yaffe, M.J.: Measurement of compressed breast thickness by optical stereoscopic photogrammetry. Med. Phys. (submitted, December 2007)
Boone, J.M., Fewell, T.R., Jennings, R.J.: Molybdenum, rhodium, and tungsten anode spectral models using interpolating polynomials with application to mammography. Med. Phys. 24(12), 1863–1874 (1997)
Boone, J.M., Lindfors, K.K., Copper III, V.N., Seibert, J.A.: Scatter/primary in mammography: Comprehensive results. Med. Phys. 27(10), 2408–2416 (2000)
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Alonzo-Proulx, O., Tyson, A.H., Mawdsley, G.E., Yaffe, M.J. (2008). Effect of Tissue Thickness Variation in Volumetric Breast Density Estimation. In: Krupinski, E.A. (eds) Digital Mammography. IWDM 2008. Lecture Notes in Computer Science, vol 5116. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-70538-3_91
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DOI: https://doi.org/10.1007/978-3-540-70538-3_91
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