Abstract
DNA computing is being applied to solve problems in combinatorial optimization, logic and Boolean circuits. Breakthrough solutions in combinatorial optimization are the most impressive area of success but, in order to solve combinatorial optimization problems, problems related to the reliability of biological operators, stable DNA expressions, processing speed, expandability and the universality of evaluation criteria must be solved. This study implements a DNA sequence generation system that minimizes errors using DNA coding based on evolutionary models and performs simulation using biological experiment operators. The usefulness of this system is evaluated by applying the Hamiltonian Path Problem (HPP) in the form of a genetic algorithm. The proposed system generates sequences with minimal errors, as compared to existing systems, and identifies optimal solutions for combinatorial optimization problems in significantly reduced processing times.
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Kashiwamura, S., Kameda, A., Yamamoto, M., Ohuchi, A.: General Protocol for Evaluating the Degree of Occurrence of Mis-hybridization. In: Proceedings of the Ninth International Symposium on Artificial Life and Robotics, AROB 9th ’04, pp. 303-308 (2004)
Shin, S.Y., Lee, I.H., Kim, D.M., Zhang, B.T.: Multiobjective Evolutionary Optimization of DNA Sequences for Reliable DNA Computing. IEEE Transactions on Evolutionary Computation 9(2), 143–158 (2005)
Faulhammer, D., Cukras, A.R., Lipton, R.J., Landweber, L.F.: Molecular Computation: RNA Solutions to Chess Problems. Proceedings of the National Academy of Science, U.S.A. 97, 1385–1389 (2000)
Tuplan, D.C., Hoose, H., Condon, A.: Stochastic Local Search Algorithms for DNA Word Design. In: Proceedings of the 8th International. Workshop on DNA Based Compuing, pp. 229–241 (2002)
Andronescu, M., Dees, D., Slaybaugh, L., Zhao, Y., Condon, A., Cohen, B., Skiena, S.: Algorithms for Testing That DNA Word Designs Avoid Unwanted Secondary Structure. In: Proc. 8th Int. Workshop DNA Based Compuing, pp. 182–195 (2002)
Feldkamp, U., Saghafi, S., Banzhaf, W., Rauhe, H.: DNA Sequence Generator - A Program for the Construction of DNA Sequences. In: Proc. 7th Int. Workshop DNA Based Computing, pp. 179–188 (2001)
Kameda, A., Yamamoto, M., Uejima, H., Hagiya, M., Sakamoto, K., Ohuchi, A.: Hairpin-based State Machine and Conformational Addressing: Design and Experiment. Natural Computing 4(2), 103–126 (2005)
Max, H.G., Russell, J.D.: Codeword Design and Information Encoding in DNA Ensembles. Natural Computing 3(3), 253–292 (2004)
Adleman, L.M.: Molecular Computation of Solutions to Combinatorial Problems. Science 266, 1021–1024 (1994)
Ansari, N.: Computational Intelligence for Optimization. Kluwer Academic Publishers, Dordrecht (1997)
Yoshikawa, T., Furuhashi, T., Uchidawa, Y.: Acquisition of Fuzzy Rules of Constructing Intelligent Systems Using Genetic Algorithm Based on DNA Coding Method. In: Proceedings of International Joint Conference of CFSA/IFIS/SOFT’95 on Fuzzy Theory and Applications (1995)
Kashiwamura, S., Kameda, A., Yamamoto, M., Ohuchi, A.: Two-step Search for DNA Sequence Design. In: Proceedings of the 2003 International Technical Conference on Circuits/Systems, Computers and Communications (ITC-CSCC 03), pp. 1815–1818 (2003)
Author information
Authors and Affiliations
Editor information
Rights and permissions
Copyright information
© 2007 Springer Berlin Heidelberg
About this paper
Cite this paper
Yin, Zx., Yang, J., Cui, Jz., Zhang, J. (2007). Evolutionary Model for Sequence Generation. In: Huang, DS., Heutte, L., Loog, M. (eds) Advanced Intelligent Computing Theories and Applications. With Aspects of Theoretical and Methodological Issues. ICIC 2007. Lecture Notes in Computer Science, vol 4681. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74171-8_2
Download citation
DOI: https://doi.org/10.1007/978-3-540-74171-8_2
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-74170-1
Online ISBN: 978-3-540-74171-8
eBook Packages: Computer ScienceComputer Science (R0)