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Blind Matrix Decomposition Techniques to Identify Marker Genes from Microarrays

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Independent Component Analysis and Signal Separation (ICA 2007)

Part of the book series: Lecture Notes in Computer Science ((LNISA,volume 4666))

Abstract

Exploratory matrix factorization methods like PCA, ICA and sparseNMF are applied to identify marker genes and classify gene expression data sets into different categories for diagnostic purposes or group genes into functional categories for further investigation of related regulatory pathways. Gene expression levels of either human breast cancer (HBC) cell lines [6] or the famous leucemia data set [10] are considered.

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Mike E. Davies Christopher J. James Samer A. Abdallah Mark D Plumbley

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© 2007 Springer-Verlag Berlin Heidelberg

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Schachtner, R. et al. (2007). Blind Matrix Decomposition Techniques to Identify Marker Genes from Microarrays. In: Davies, M.E., James, C.J., Abdallah, S.A., Plumbley, M.D. (eds) Independent Component Analysis and Signal Separation. ICA 2007. Lecture Notes in Computer Science, vol 4666. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74494-8_81

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  • DOI: https://doi.org/10.1007/978-3-540-74494-8_81

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-74493-1

  • Online ISBN: 978-3-540-74494-8

  • eBook Packages: Computer ScienceComputer Science (R0)

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