Abstract
A long-term durability of a ventricular assist device (VAD) is required due to a shortage of donor hearts for cardiac transplantation, but there is no analyzed pump data after long-term use. This study aimed to perform a comparative study between new VAD and VADs after long-term use. The hydrodynamic performance of the used Toyobo VADs (mean period of 5 months with the maximum of 12 months) was evaluated in a mock circulatory system, where a new VAD was used as a control. Although a remarkable difference was not observed in terms of mean flow rate, flow and pressure waveforms varied significantly. Then, the pressure-volume relationship of each pump was measured. It was found that the capacity of long-term VADs was reduced. Although a further study is required, these results suggested that a long-term use of VAD may cause a change in mechanical properties of polymer materials.
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© 2007 Springer-Verlag Berlin Heidelberg
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Kokuzawa, Y. et al. (2007). Investigation of a Hydrodynamic Performance of a Ventricular Assist Device After Its Long-Term Use in Clinical Application. In: Li, K., Li, X., Irwin, G.W., He, G. (eds) Life System Modeling and Simulation. LSMS 2007. Lecture Notes in Computer Science(), vol 4689. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74771-0_49
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DOI: https://doi.org/10.1007/978-3-540-74771-0_49
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-74770-3
Online ISBN: 978-3-540-74771-0
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