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Investigation of a Hydrodynamic Performance of a Ventricular Assist Device After Its Long-Term Use in Clinical Application

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Life System Modeling and Simulation (LSMS 2007)

Abstract

A long-term durability of a ventricular assist device (VAD) is required due to a shortage of donor hearts for cardiac transplantation, but there is no analyzed pump data after long-term use. This study aimed to perform a comparative study between new VAD and VADs after long-term use. The hydrodynamic performance of the used Toyobo VADs (mean period of 5 months with the maximum of 12 months) was evaluated in a mock circulatory system, where a new VAD was used as a control. Although a remarkable difference was not observed in terms of mean flow rate, flow and pressure waveforms varied significantly. Then, the pressure-volume relationship of each pump was measured. It was found that the capacity of long-term VADs was reduced. Although a further study is required, these results suggested that a long-term use of VAD may cause a change in mechanical properties of polymer materials.

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References

  1. Fukushima, N., Matsuda, H.: Heart transplantation in Japan. Nippon Rinsho 61(6), 1057–1062 (2003)

    Google Scholar 

  2. Masai, T., Shimazaki, Y., Kadoda, K., Miyamoto, Y., Sawa, Y., Yagura, A., Matsuda, H., Sato, M., Kashiwabara, S.: Clinical experience with long-term use of the Toyobo left ventricular assist system. ASIO J. 41(3), M522–525 (1995)

    Article  Google Scholar 

  3. Seki, T., Kitamura, S., Kawachi, K., Fukutomi, M., Kobayashi, S., Kawata, T., Niwaya, K., Morita, R.: Efficacy and limitation of a left ventricular assist system in a patient with dilated cardiomyopathy accompanying multi-organ dysfunction. J. Cardiovasc. Surg. 36(2), 147–151 (1995)

    Google Scholar 

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Kang Li Xin Li George William Irwin Gusen He

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© 2007 Springer-Verlag Berlin Heidelberg

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Kokuzawa, Y. et al. (2007). Investigation of a Hydrodynamic Performance of a Ventricular Assist Device After Its Long-Term Use in Clinical Application. In: Li, K., Li, X., Irwin, G.W., He, G. (eds) Life System Modeling and Simulation. LSMS 2007. Lecture Notes in Computer Science(), vol 4689. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74771-0_49

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  • DOI: https://doi.org/10.1007/978-3-540-74771-0_49

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-74770-3

  • Online ISBN: 978-3-540-74771-0

  • eBook Packages: Computer ScienceComputer Science (R0)

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