Abstract
This paper proposes a systematic approach to integrate domain-dependent design tools in artificial bone scaffolds process. Integrated solution of CAD modelling and properly analysis of biomedicine knowledge are utilized to design complicated bone scaffolds. FEA and CFD are comprehensively analyzed for the mechanical and internal micro circulation properties. A case study of a successful artificial bone scaffolds model demonstrates that the cooperative design methodology can facilitate the design in the multi-physics domain substantially.
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References
Rifai, S.M., et al.: Automotive design applications of fluid flow simulation on parallel computing platforms. Computer Methods in Applied Mechanics and Engineering 184(2-4), 449–466 (2000)
Gunaratne, G.H., et al.: Model for Bone Strength and Osteoporotic Fractures. Physical Review Letters 88(6), 068101-1-068101-4 (2002)
Rubin, C., Judex, S., Hadjiargyrou, M.: Skeletal adaptation to mechanical stimuli in the absence of formation or resorption of bone. Musculoskel Neuron Interact 2(3), 264–267 (2002)
Thomas, G.P., Haj, A.J.E.: Bone Marrow Stromal Cells are Load Responsive. Vitro. Calcified Tissue International 58(2), 101–108 (1996)
Werner, J., et al.: Mechanical properties and in vitro cell compatibility of hydroxyapatite ceramics with graded pore structure. Biomaterials 23(21), 4285–4294 (2002)
Sigmund, O.: Design of multiphysics actuators using topology optimization - Part I: One-material structures. Computer Methods in Applied Mechanics and Engineering 190(49-50), 6577–6604 (2001)
Huang, J., et al.: Bi-objective optimization design of functionally gradient materials. Materials & Design 23(7), 657–666 (2002)
Guest, J.K., Prevost, J.H.: Optimizing multifunctional materials: Design of microstructures for maximized stiffness and fluid permeability. International Journal of Solids and Structures 43(22-23), 7028–7047 (2006)
Wang, Y.E., et al.: Integration of collaborative design and process planning for artificial bone scaffold 3D printer nozzle. Cooperative Design, Visualization, and Engineering, Proceedings, pp. 132–140 (2000)
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Wang, Y., Wei, S., Yan, X., Zeng, Q. (2007). Integrating Domain Dependent Tools in Artificial Bone Scaffolds Design. In: Luo, Y. (eds) Cooperative Design, Visualization, and Engineering. CDVE 2007. Lecture Notes in Computer Science, vol 4674. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74780-2_40
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DOI: https://doi.org/10.1007/978-3-540-74780-2_40
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-74779-6
Online ISBN: 978-3-540-74780-2
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