Abstract
It is well understood that populations cannot grow without bound and that it is competition between individuals for resources which restricts growth. Despite centuries of interest, the question of how best to model density dependent population growth still has no definitive answer. We address this question here through a number of individual based models of populations expressed using the process algebra WSCCS. The advantage of these models is that they can be explicitly based on observations of individual interactions. From our probabilistic models we derive equations expressing overall population dynamics, using a formal and rigorous rewriting based method. These equations are easily compared with the traditionally used deterministic Ordinary Differential Equation models and allow evaluation of those ODE models, challenging their assumptions about system dynamics. Further, the approach is applied to epidemiology, combining population growth with disease spread.
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Malthus, T.: An essay on the principle of population (1798)
Verhulst, P.: Notice sur la loi que la population suit dans son accroissement. Corr. Math. et Phys. 10, 113–121 (1838)
Beverton, R., Holt, S.: On the dynamics of exploited fish populations. Fisheries Investigations, Series 2. H.M.S.O., vol. 19 (1957)
Gompertz, B.: On the nature of the function expressive of the law of human mortality, and on a new mode of determining the value of life contingencies. Philosophical transactions of the Royal Society of London Series B 115, 513–585 (1825)
Hassell, M.: Density-dependence in single-species populations. Journal of Animal Ecology 45, 283–296 (1975)
Ricker, W.: Stock and recruitement. Journal of the Fisheries Research Board of Canada 11, 559–623 (1954)
Calder, M., Gilmore, S., Hillston, J.: Modelling the influence of RKIP on the ERK signalling pathway using the stochastic process algebra PEPA. In: Proceedings of BioCONCUR 2004. Electronic Notes in Theoretical Computer Science. Elsevier, Amsterdam (2004)
Norman, R., Shankland, C.: Developing the use of process algebra in the derivation and analysis of mathematical models of infectious disease. In: Moreno-DÃaz Jr., R., Pichler, F. (eds.) EUROCAST 2003. LNCS, vol. 2809, pp. 404–414. Springer, Heidelberg (2003)
Regev, A., Panina, E., Silverman, W., Cardelli, L., Shapiro, E.: Bioambients: an abstraction for biological compartments. Theoretical Computer Science 325, 141–167 (2004)
Sumpter, D.: From Bee to Society: an agent based investigation of honeybee colonies. PhD thesis, UMIST (2000)
Tofts, C.: Using process algebra to describe social insect behaviour. Transactions of the Society for Computer Simulation 9, 227–283 (1993)
Tofts, C.: Processes with probabilities, priority and time. Formal Aspects of Computing 6, 536–564 (1994)
McCaig, C.: From individuals to populations: changing scale in process algebra models of biological systems. PhD thesis, University of Stirling (2008), www.cs.stir.ac.uk/~cmc/thesis.ps
McCaig, C., Norman, R., Shankland, C.: Deriving mean field equations from process algebra models. Technical Report 175, University of Stirling (2008), www.cs.stir.ac.uk/research/publications/techreps
Brännström, A., Sumpter, D.: The role of competition and clustering in population dynamics. Proceedings of the Royal Society of London Series B 272, 2065–2072 (2005)
Calder, M., Gilmore, S., Hillston, J.: Automatically deriving ODEs from process algebra models of signalling pathways. In: Proceedings of CMSB 2005 (Computational Methods in Systems Biology), pp. 204–215 (2005)
Hillston, J.: Fluid Flow Approximation of PEPA models. In: QEST 2005, Proceedings of the 2nd International Conference on Quantitative Evaluation of Systems, pp. 33–42. IEEE Computer Society Press, Torino (2005)
Cardelli, L.: On process rate semantics. Theoretical Computer Science 391, 190–215 (2008)
Milner, R.: Communication and Concurrency. Prentice Hall, Englewood Cliffs (1989)
Begon, M., Bennet, M., Bowers, R., French, N., Hazel, S., Turner, J.: A clarification of transmission terms in host-microparasite models: numbers, densities and areas. Epidemiology and infection 129, 147–153 (2002)
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McCaig, C., Norman, R., Shankland, C. (2008). Process Algebra Models of Population Dynamics. In: Horimoto, K., Regensburger, G., Rosenkranz, M., Yoshida, H. (eds) Algebraic Biology. AB 2008. Lecture Notes in Computer Science, vol 5147. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-85101-1_11
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DOI: https://doi.org/10.1007/978-3-540-85101-1_11
Publisher Name: Springer, Berlin, Heidelberg
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