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Part of the book series: Lecture Notes in Computer Science ((LNTCS,volume 5518))

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Abstract

The genetic code is the translation table used by an organism to transform each nucleotide triplet (codon) into an amino acid. For any species, its genetic code can be predicted by comparing conserved codon sites in protein alignments of target and reference sequences. Here we describe the design and implementation of a general and improved dynamic pipeline to predict the genetic code for any genome/species, taking into account the physicochemical properties of the amino acids involved and the phylogenetic relationships of the organisms compared.

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References

  1. Abascal, F., Posada, D., Knight, R.D., Zardoya, R.: Parallel evolution of the genetic code in arthropod mitochondrial genomes. PloS Biology 4(5), e127 (2006)

    Article  Google Scholar 

  2. Abascal, F., Zardoya, R., Posada, D.: GenDecoder: genetic code prediction for metazoan mitochondria. Nucleic Acids Research 34, W389–W393 (2006)

    Article  Google Scholar 

  3. Knight, R.D., Freeland, S.J., Landweber, L.F.: Nat. Rev. Genet. 2, 49–58 (2001)

    Article  Google Scholar 

  4. Yokobori, S., Suzuki, T., Watanabe, K.: J. Mol. Evol. 53, 314–326 (2001)

    Article  Google Scholar 

  5. Ivanov, V., Beniaminov, A., Mikheyev, A., Minyat, E.: Rna 7, 1683–1692 (2001)

    Google Scholar 

  6. Beagley, C.T., Okimoto, R., Wolstenholme, D.R.: Genetics 148, 1091–1108 (1998)

    Google Scholar 

  7. Barrell, B.G., Bankier, A.T., Drouin, J.: Nature 282, 189–194 (1979)

    Article  Google Scholar 

  8. Telford, M.J., Herniou, E.A., Russell, R.B., Littlewood, D.T.: Proc. Natl. Acad. Sci. U S A 97, 11359–11364 (2000)

    Article  Google Scholar 

  9. Gabaldón, T.: Comparative genomics-based prediction of protein function. Methods in Molecular Biology 439, 387–401

    Google Scholar 

  10. Katoh, K., Misawa, K., Kuma, K., Miyata, T.: MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform. Nucleic Acid Research 30, 3059–3066 (2002)

    Article  Google Scholar 

  11. Lowe, T.M., Eddy, S.R.: tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence. Nucleic Acids Research 25, 955–964 (1997)

    Article  Google Scholar 

  12. Telford, M.J., Herniou, E.A., Russell, R.B., Littlewood, D.T.: Changes in mitochondrial genetic codes as phylogenetic characters: Two examples from the flatworms. Proc. Natl. Acad. Sci. USA 97(21), 11359–11364 (2000)

    Article  Google Scholar 

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© 2009 Springer-Verlag Berlin Heidelberg

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Patricio, M., Huerta-Cepas, J., Gabaldón, T., Zardoya, R., Posada, D. (2009). Automatic Prediction of the Genetic Code. In: Omatu, S., et al. Distributed Computing, Artificial Intelligence, Bioinformatics, Soft Computing, and Ambient Assisted Living. IWANN 2009. Lecture Notes in Computer Science, vol 5518. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02481-8_170

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  • DOI: https://doi.org/10.1007/978-3-642-02481-8_170

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-02480-1

  • Online ISBN: 978-3-642-02481-8

  • eBook Packages: Computer ScienceComputer Science (R0)

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