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Biotin-Streptavidin Sensitive BioFETs and Their Properties

  • Conference paper
Biomedical Engineering Systems and Technologies (BIOSTEC 2009)

Part of the book series: Communications in Computer and Information Science ((CCIS,volume 52))

Abstract

In this work the properties of a biotin-streptavidin BioFET have been studied numerically with homogenized boundary interface conditions as the link between the oxide of the FET and the analyte which contains the bio-sample. The biotin-streptavidin reaction pair is used in purification and detection of various biomolecules; the strong streptavidin-biotin bond can also be used to attach biomolecules to one another or onto a solid support. Thus this reaction pair in combination with a FET as the transducer is a powerful setup enabling the detection of a wide variety of molecules with many advantages that stem from the FET, like no labeling, no need of expensive read-out devices, the possibility to put the signal amplification and analysis on the same chip, and outdoor usage without the necessity of a lab.

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Authors and Affiliations

  1. Institute for Microelectronics, TU Wien, Gußhaustraße 27–29/E360, A-1040, Wien, Austria

    Thomas Windbacher, Viktor Sverdlov & Siegfried Selberherr

Authors
  1. Thomas Windbacher
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  2. Viktor Sverdlov
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  3. Siegfried Selberherr
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Editor information

Editors and Affiliations

  1. Instituto de Telecomunicaçöes, IST - Instituto Superior Técnico, Av. Rovisco Pais, 1, 1049-001, Portugal, Lisbon

    Ana Fred

  2. Departament of Systems and Informatics, Polytechnic Institute of Setúbal – INSTICC, Rua do Vale de Chaves - Estefanilha, 2910-761, Setúbal, Portugal

    Joaquim Filipe

  3. Institute of Telecommunications, Av. Rovisco Pais, 1, 1049-001, Lisboa, Portugal

    Hugo Gamboa

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Windbacher, T., Sverdlov, V., Selberherr, S. (2010). Biotin-Streptavidin Sensitive BioFETs and Their Properties. In: Fred, A., Filipe, J., Gamboa, H. (eds) Biomedical Engineering Systems and Technologies. BIOSTEC 2009. Communications in Computer and Information Science, vol 52. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11721-3_6

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  • DOI: https://doi.org/10.1007/978-3-642-11721-3_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-11720-6

  • Online ISBN: 978-3-642-11721-3

  • eBook Packages: Computer ScienceComputer Science (R0)

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