Abstract
The identity and function of a cell is determined by its entire RNA component, which is called the transcriptome of a cell. The transcriptome is the functional readout of the genome and epigenome. In an organism, essentially every cell has the same genome, while every cell type and potentially each individual cell has a unique transcriptome. Ideally, the transcriptome analysis should capture the exact quantity of all full length RNAs of all classes at single-base resolution in the smallest functional unit of an organism, an individual cell.
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Barbacioru, C. (2010). Tracing the Early Cell Divisions of Mouse Embryos by Single Cell RNA-Seq. In: Borodovsky, M., Gogarten, J.P., Przytycka, T.M., Rajasekaran, S. (eds) Bioinformatics Research and Applications. ISBRA 2010. Lecture Notes in Computer Science(), vol 6053. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-13078-6_1
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DOI: https://doi.org/10.1007/978-3-642-13078-6_1
Publisher Name: Springer, Berlin, Heidelberg
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