Abstract
In this paper we present a novel classification method of SPECT images for the early diagnosis of the Alzheimer’s disease (AD). The proposed method is based on Association Rules (ARs) aiming to discover interesting associations between attributes contained in the database. The system uses firstly voxel-as-features (VAF) and Activation Estimation (AE) to find tridimensional activated brain regions of interest (ROIs) for each patient. These ROIs act as inputs to secondly mining ARs between activated blocks for controls, with a specified minimum support and minimum confidence. ARs are mined in supervised mode, using information previously extracted from the most discriminant rules for centering interest in the relevant brain areas, reducing the computational requirement of the system. Finally classification process is performed depending on the number of previously mined rules verified by each subject, yielding an up to 95.87% classification accuracy, thus outperforming recent developed methods for AD diagnosis.
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Chaves, R. et al. (2010). Effective Diagnosis of Alzheimer’s Disease by Means of Association Rules. In: Graña Romay, M., Corchado, E., Garcia Sebastian, M.T. (eds) Hybrid Artificial Intelligence Systems. HAIS 2010. Lecture Notes in Computer Science(), vol 6076. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-13769-3_55
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DOI: https://doi.org/10.1007/978-3-642-13769-3_55
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