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Part of the book series: Advances in Intelligent and Soft Computing ((AINSC,volume 77))

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Abstract

Standard data analysis techniques for biomedical problems cannot take into account existing prior knowledge, and available literature results cannot be incorporated in further studies. In this work we review some techniques that incorporate prior knowledge in supervised classification algorithms as constraints to the underlying optimization and linear algebra problems. We analyze a case study, to show the advantage of such techniques in terms of prediction accuracy.

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References

  1. Bishop, C.M.: Neural networks for pattern recognition. Oxford University Press, Oxford (1995)

    Google Scholar 

  2. Bjork, A.: Numerical methods for least squares. SIAM, Philadelphia (1996)

    Google Scholar 

  3. Golub, G., van Loan, C.: Matrix Computations, 3rd edn. Johns Hopkins University Press, Baltimore (1996)

    MATH  Google Scholar 

  4. Golub, G.H., Underwood, R.: Stationary values of the ratio of quadratic forms subject to linear constraints. Z. Angew. Math. Phys (ZAMP) 21(3), 318–326 (1970)

    Article  MATH  MathSciNet  Google Scholar 

  5. Guarracino, M., Abbate, D., Prevete, R.: Nonlinear knowledge in learning models. In: Proceedings of Workshop on Prior Conceptual Knowledge in Machine Learning and Knowledge Discovery, European Conference on Machine Learning, pp. 29–40 (2007), http://www.ecmlpkdd2007.org/CD/workshops/PRICKLWM2/P_Gua/GuarracinoPriCKL/Guarracino.pdf

  6. Guarracino, M.R., Cifarelli, C., Seref, O., Pardalos, P.: A classification method based on generalized eigenvalue problems. Optim. Methods Softw. 22, 73–81 (2007)

    Article  MATH  MathSciNet  Google Scholar 

  7. Lee, Y., Mangasarian, O.L.: Ssvm: A smooth support vector machine for classification (1999), http://citeseer.ist.psu.edu/lee99ssvm.html

  8. Mangasarian, O.L., Wild, E.W.: Multisurface proximal support vector classification via generalized eigenvalues. Tech. Rep. 04-03, Data Mining Institute (2004)

    Google Scholar 

  9. Mangasarian, O.L., Wild, E.W.: Nonlinear knowledge-based classification. Tech. rep., Data Mining Institute Technical Report 06-04, Computer Science Department, University of Wisconsin, Madison, Wisconsin (2006)

    Google Scholar 

  10. Pardalos, P.M., Abbate, D., Guarracino, M.R., Chinchuluun, A.: Neural network classification with prior knowledge for analysis of biological data. In: Proceedings of the International Symposium on Mathematical and Computational Biology, Biomat 2008, Brazil, pp. 223–234. World Scientific, Singapore (2008)

    Google Scholar 

  11. Schölop, B., Smola, A.: Learning with Kernels: Support Vector Machines, Regularization, Optimization, and Beyond. MIT Press, Cambridge (2001)

    Google Scholar 

  12. Vapnik, V.: The Nature of Statistical Learning Theory. Springer, New York (1995)

    MATH  Google Scholar 

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Abbate, D., De Asmundis, R., Guarracino, M.R. (2010). Prior Knowledge in the Classification of Biomedical Data. In: Borgelt, C., et al. Combining Soft Computing and Statistical Methods in Data Analysis. Advances in Intelligent and Soft Computing, vol 77. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-14746-3_1

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  • DOI: https://doi.org/10.1007/978-3-642-14746-3_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-14745-6

  • Online ISBN: 978-3-642-14746-3

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