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International Conference on Artificial Intelligence: Methodology, Systems, and Applications

AIMSA 2010: Artificial Intelligence: Methodology, Systems, and Applications pp 281–282Cite as

Feed Rate Profiles Synthesis Using Genetic Algorithms

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Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 6304))

Abstract

In the paper a genetic algorithm for feed rate profiles synthesis is proposed. An E. coli fed-batch fermentation process is considered. The feed rate profiles based on three different lengths of chromosomes are synthesized. A satisfactory result for the fermentation system due to economical effect and process effectiveness is achieved.

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References

  1. Arndt, M., Hitzmann, B.: Feed Forward/Feedback Control of Glucose Concentration during Cultivation of Escherichia coli. In: 8th IFAC Int. Conf. on Comp. Appl. in Biotechn., Quebec City, Canada, pp. 425–429 (2001)

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  2. Chen, L.Z., Nguang, S.K., Chen, X.D.: On-line Identification and Optimization of Feed Rate Profiles for High Productivity Fed-batch Culture of Hybridoma Cells using Genetic Algorithms. ISA Trans. 41(4), 409–419 (2002)

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  3. Roeva, O.: Parameter Estimation of a Monod-type Model based on Genetic Algorithms and Sensitivity Analysis. In: Lirkov, I., Margenov, S., Waśniewski, J. (eds.) LSSC 2007. LNCS, vol. 4818, pp. 601–608. Springer, Heidelberg (2008)

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  4. Roeva, O., Tzonkov, S.: A Genetic Algorithm for Feeding Trajectory Optimization of Fed-batch Fermentation Processes. Int. J. Bioautomation 12, 1–12 (2009)

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  5. Shin, H.S., Lim, H.C.: Maximization of Metabolite in Fed-batch Cultures Sufficient Conditions for Singular Arc and Optimal Feed Rate Profiles. Biochemical Eng. J. 37, 62–74 (2007)

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Author information

Authors and Affiliations

  1. Centre of Biomedical Engineering, Bulgarian Academy of Sciences, 105 Acad. G. Bonchev Str., Sofia, 1113, Bulgaria

    Olympia Roeva

Authors
  1. Olympia Roeva
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Editor information

Editors and Affiliations

  1. Winston-Salem State University, 601 S. Martin Luther King Drive, NC 27110, Winston Salem, USA

    Darina Dicheva

  2. Institute of Information Technologies, Bulgarian Academy of Sciences, 29A Acad. Bonchev Str., 1113, Sofia, Bulgaria

    Danail Dochev

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© 2010 Springer-Verlag Berlin Heidelberg

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Roeva, O. (2010). Feed Rate Profiles Synthesis Using Genetic Algorithms. In: Dicheva, D., Dochev, D. (eds) Artificial Intelligence: Methodology, Systems, and Applications. AIMSA 2010. Lecture Notes in Computer Science(), vol 6304. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-15431-7_37

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  • DOI: https://doi.org/10.1007/978-3-642-15431-7_37

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-15430-0

  • Online ISBN: 978-3-642-15431-7

  • eBook Packages: Computer ScienceComputer Science (R0)

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