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Diagnosis of Liver Diseases from P31 MRS Data Based on Feature Selection Using Genetic Algorithm

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Life System Modeling and Intelligent Computing (ICSEE 2010, LSMS 2010)

Abstract

P31 MRS technique is important either in diagnosis or in treatment of many hepatic diseases for it can provides non-invasive information about the chemical content of the energy metabolism in cellular level. The data samples from P31 MRS are classified into three types of hepatocellular carcinoma, hepatic cirrhosis and normal hepatic tissue using computational intelligence methods. A genetic algorithm is used as main feature selection method and the Gaussian model is selected in the mutation operation. Two classification algorithms are used which consist of fisher linear discriminant analysis and quadratic discriminant analysis. Experiments show that the application of genetic algorithm and fisher linear classifier offers more reliable information for diagnostic prediction of liver cancer in vivo. And when the cross-validation method is 10-fold model, this algorithm can improve the average recognition correction rate of three types to 94.28%.

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References

  1. Griffiths, J.R., Stevens, A.N., Iles, R.A., et al.: 31P-NMR investigation of solid tumours in the living rat. Biosci. Rep. 4, 319–325 (1981)

    Article  Google Scholar 

  2. Griffiths, J.R., et al.: 31P-NMR studies of a human tumour in situ. Lancet 8339, 1435–1436 (1983)

    Article  Google Scholar 

  3. Fukunnaga, K.: Introduction to Statistical Pattern Recognition, 2nd edn. Academic Press, London (1991)

    Google Scholar 

  4. Holland, J.H.: Adaptation in Natural and Artificial Systems. University of Michigan press, Ann Arbor (1992)

    Google Scholar 

  5. Whitley, D.: The GENITOR algorithm and selection pressure: why rank-based allocation of reproductive trials is best. In: ICGA3, San Mateo, pp. 116–121 (1989)

    Google Scholar 

  6. Mills, G.C.: The molecular evolutionary clock: a critique. Perspectives on Science and Christian Faith. 46, 159–168 (1994)

    Google Scholar 

  7. Belhumeur, P.N., Hespanha, J.P., Kriegman, D.J.: Eigenfaces vs. Fisherfaces: recognition using class specific linear projection. IEEE Trans. Pattern Anal. Mach. Intell. 19(7), 711–720 (1997)

    Article  Google Scholar 

  8. Martinez, A.M., Kak, A.C.: PCA Versus LDA. IEEE Trans., Pattern Anal. Mach. Intell. 23(2), 228–233 (2001)

    Article  Google Scholar 

  9. Fisher, R.A.: The Use of Multiple Measures in Taxonomic Problems. Ann. Eugenics 7, 179–188 (1936)

    Google Scholar 

  10. Ye, J.P., Janardan, R., Park, C.H., Park, H.: An Optimization Criterion for Generalized Discriminant Analysis on Undersampled Problems. IEEE Trans. Pattern Anal. Mach. Intell. 26(8), 982–994 (2004)

    Article  Google Scholar 

  11. Zhao, W., Chellappa, R., Phillips, J., Rosenfeld, A.: Face Recognition: A Literature Survey. ACM Computing Surveys 35(4), 399–458 (2003)

    Article  Google Scholar 

  12. Bishop, C.: Neural networks for pattern recognition. Oxford University Press, Oxford (1995)

    Google Scholar 

  13. McLachlan, G.J.: Discriminant Analysis and Statistical Pattern Recognition. John Wiley, New York (1992)

    Book  Google Scholar 

  14. Fisher, R.A.: The use of multiple measurements in taxonomic problems. Ann Eugene 7, 79–188 (1936)

    Google Scholar 

  15. Krzanowski, W.J.: Principles of Multivariate Analysis, vol. 347. Clarendon Press, Oxford (1993)

    Google Scholar 

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© 2010 Springer-Verlag Berlin Heidelberg

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Cheng, J., Liu, Y., Sang, J., Liu, Q., Wang, S. (2010). Diagnosis of Liver Diseases from P31 MRS Data Based on Feature Selection Using Genetic Algorithm. In: Li, K., Jia, L., Sun, X., Fei, M., Irwin, G.W. (eds) Life System Modeling and Intelligent Computing. ICSEE LSMS 2010 2010. Lecture Notes in Computer Science(), vol 6330. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-15615-1_15

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  • DOI: https://doi.org/10.1007/978-3-642-15615-1_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-15614-4

  • Online ISBN: 978-3-642-15615-1

  • eBook Packages: Computer ScienceComputer Science (R0)

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