Skip to main content

Interactive Cardiac Image Analysis for Biventricular Function of the Human Heart

  • Conference paper
Statistical Atlases and Computational Models of the Heart (STACOM 2010)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 6364))

Abstract

We developed an interactive tool for biventricular function analysis from cardiac magnetic resonance (MR) images based on the guide point modelling (GPM) approach [1]. First we built a deformable model of both ventricles of the human heart which consisted of 138 nodes and 82 hexahedral elements, each with bicubic-Bézier-linear interpolation. The model was fitted to a digitized human data set for use as the prior shape in the GPM scheme, which we modified to have a ‘predictor’ step that used a host mesh fitting algorithm [2] to generate predicted points (PPs) based on the user-defined guide points (GPs). Then the model was fitted towards both GPs and PPs through linear least square minimization. The inclusion of the PPs significantly improved the numerical stability of the linear least square fit and significantly accelerated the solution time. This methodology requires further validation for future application in clinical biventricular analysis.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Young, A.A., Cowan, B.R., Thrupp, S.F., Hedley, W.J., Dell’Italia, L.J.: Left Ventricular Mass and Volume: Fast Calculation with Guide-Point Modeling on MR Images. Radiology 216, 597–602 (2000)

    Google Scholar 

  2. Fernandez, J.W., Mithraratne, P., Thrupp, S.F., Tawhai, M.H., Hunter, P.J.: Anatomically Based Geometric Modelling of the Musculo-Skeletal System and Other Organs. Biomech. Model. Mechanobiol. 2, 139–155 (2003)

    Article  Google Scholar 

  3. Nagel, E., Stuber, M., Hess, O.M.: Importance of the Right Ventricle in Valvular Heart Disease. Eur. Heart J. 17, 829–836 (1996)

    Google Scholar 

  4. Lilly, L.S. (ed.): Pathophysiology of Heart Disease: A Collaborative Project of Medical Students and Faculty, 2nd edn. Williams & Wilkins, USA (1998)

    Google Scholar 

  5. Lorenzo-Valdes, M., Sanchez-Ortiza, G., Elkingtonb, A., Mohiaddinb, R., Rueckert, D.: Segmentation of 4D Cardiac MR Images Using a Probabilistic Atlas and the EM Algorithm. Med. Image Anal. 8, 255–265 (2004)

    Article  Google Scholar 

  6. Cocosco, C.A., Niessen, W.J., Netsch, T., Vonken, E.J., Lund, G., Stork, A., Viergever, M.A.: Automatic Image-Driven Segmentation of the Ventricles in Cardiac Cine MRI. J. Magn. Reson. Imaging 28, 366–374 (2008)

    Article  Google Scholar 

  7. Sermesant, M., Forest, C., Pennec, X., Delingette, H., Ayache, N.: Deformable Biomechanical Models: Application to 4D Cardiac Image Analysis. Medical Image Analysis 7(4), 475–488 (2003)

    Article  Google Scholar 

  8. Lötjönen, J., Kivistö, S., Koikkalainen, J., Smutek, D., Lauerma, K.: Statistical Shape Model of Atria, Ventricles and Epicardium from Short- and Long-Axis MR Images. Med. Image Anal. 8, 371–386 (2004)

    Article  Google Scholar 

  9. Bistoquet, A., Oshinski, J., Skrinjar, O.: Left Ventricular Deformation Recovery from Cine MRI using an Incompressible Model. IEEE Trans. Med. Imag. 26(9), 1136–1153 (2007)

    Article  Google Scholar 

  10. Zhang, H., Wahle, A., Johnson, R.K., Scholz, T.D., Sonka, M.: 4-D Cardiac MR Image Analysis: Left and Right Ventricular Morphology and Function. IEEE Trans. Med. Imaging 29(2), 350–364 (2010)

    Article  Google Scholar 

  11. Stevens, C., Remme, E., LeGrice, I., Hunter, P.: Ventricular Mechanics in Diastole: Material Parameter Sensitivity. J. Biomech. 36(5), 737–748 (2003)

    Article  Google Scholar 

  12. Nielsen, P.M.F., LeGrice, I.J., Smaill, B.H., Hunter, P.J.: Mathematical Model of Geometry and Fibrous Structure of the Heart. Am. J. Physiol. 260, H1365–H1378 (1991)

    Google Scholar 

  13. LeGrice, I.J., Hunter, P.J., Smaill, B.H.: Laminar Structure of the Heart: a Mathematical Model. Am. J. Physiol. 272, H2466–H2476 (1997)

    Google Scholar 

  14. Kerckhoffs, R.C.P., Bovendeerd, P.H.M., Prinzen, F.W., Smits, K., Arts, T.: Intra- and Interventricular Asynchrony of Electromechanics in the Ventricularly Paced Heart. J. Eng. Math. 47, 201–216 (2003)

    Article  MATH  MathSciNet  Google Scholar 

  15. Vetter, F.J., McCulloch, A.D.: Three-Dimensional Analysis of Regional Cardiac Function: a Model of Rabbit Ventricular Anatomy. Prog. Biophys. Mol. Biol. 69, 157–183 (1998)

    Article  Google Scholar 

  16. Nielsen, P.M.F.: The Anatomy of the Heart: A Finite Element Model. PhD Thesis, University of Auckland (1987)

    Google Scholar 

  17. Li, B., Young, A.A., Cowan, B.R.: GPU Accelerated Non-rigid Registration for the Evaluation of Cardiac Function. Med. Image Comput. Comput. Assist. Interv. 11(Pt. 2), 880–887 (2008)

    Google Scholar 

  18. Singleton, H.R., Pohost, G.M.: Automatic Cardiac MR Segmentation using Edge Detection by Tissue Classification in Pixel Neighborhoods. Magn. Reson. Med. 37, 418–424 (1997)

    Article  Google Scholar 

  19. Trefethen, L.N., Bau III, D.: Numerical Linear Algebra. S.I.A.M., Philadelphia (1997)

    MATH  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Lam, HI., Cowan, B.R., Nash, M.P., Young, A.A. (2010). Interactive Cardiac Image Analysis for Biventricular Function of the Human Heart. In: Camara, O., Pop, M., Rhode, K., Sermesant, M., Smith, N., Young, A. (eds) Statistical Atlases and Computational Models of the Heart. STACOM 2010. Lecture Notes in Computer Science, vol 6364. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-15835-3_15

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-15835-3_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-15834-6

  • Online ISBN: 978-3-642-15835-3

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics