Abstract
Distinguishing pulmonary arterial and venous (A/V) trees via in vivo imaging is essential for quantification of vascular geometry useful to diagnose several pulmonary diseases. A multi-scale topo-morphologic opening algorithm has recently been introduced separating A/V trees via non-contrast CT imaging. The method starts with two sets of seeds — one for each of A/V trees and combines fuzzy distance transform, fuzzy connectivity, and morphologic reconstruction leading to locally-adaptive multi-scale opening of two mutually fused structures. Here, we present results of a comprehensive validation study assessing both reproducibility and accuracy of the method. Accuracy of the method is examined using both mathematical phantoms and CT images of contrast-separated pulmonary A/V casting of a pig’s lung. Reproducibility of the method is evaluated using multi-user A/V separations of patients’s CT pulmonary data and contrast-enhanced CT data of a pig’s lung at different volumes. The qualitative and quantitative results are very promising.
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Gao, Z., Holtze, C., Grout, R., Sonka, M., Hoffman, E., Saha, P.K. (2010). Multi-scale Topo-morphometric Opening of Arteries and Veins: An Evaluative Study via Pulmonary CT Imaging. In: Bebis, G., et al. Advances in Visual Computing. ISVC 2010. Lecture Notes in Computer Science, vol 6455. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-17277-9_14
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DOI: https://doi.org/10.1007/978-3-642-17277-9_14
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