Abstract
We used the software Optferm to model and optimize the bioprocess of escherichia coli fermentation, simulating the conditions of a fed-batch bioreactor. The results, obtained by employing different AI approaches, provided useful orientation for nutrient feed strategies for increased productivity. In conclusion, we believe in silico tools can perform a rapid and valid optimization of bioprocesses avoiding expensive experiments.
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Teixeira, T., Deusdado, S. (2011). Experiments on Computer Assisted Optimization of the Escherichia Coli Fermentation Process Using Optferm. In: Rocha, M.P., Rodríguez, J.M.C., Fdez-Riverola, F., Valencia, A. (eds) 5th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2011). Advances in Intelligent and Soft Computing, vol 93. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-19914-1_11
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DOI: https://doi.org/10.1007/978-3-642-19914-1_11
Publisher Name: Springer, Berlin, Heidelberg
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