Abstract
The dynamics of the hybridization process in microarrays experiments is complex as thermodynamics factors influencing molecular interaction are still fields of important research and their effects are not fully taken into account in the estimation of genetic expression. In this paper an adaptive fitting is used to predict and regress microarray expression levels on a specific test probe to common thermodynamic conditions.
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Malutan, R., Vilda, P.G., Neagoe, I.B., Borda, M. (2011). Hybridization Dynamics Compensation in Microarray Experiments. In: Rocha, M.P., Rodríguez, J.M.C., Fdez-Riverola, F., Valencia, A. (eds) 5th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2011). Advances in Intelligent and Soft Computing, vol 93. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-19914-1_34
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DOI: https://doi.org/10.1007/978-3-642-19914-1_34
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-19913-4
Online ISBN: 978-3-642-19914-1
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