Abstract
A model is here presented to analyse how vesicles may turn into protocells that synthesize their own lipid components and the consequences that this may have on the properties of the resulting membrane (in particular, on its permeability), as well as on the overall stability of the system.
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Berclaz, N., Mueller, M., Walde, P., Luisi, P.L.: Growth and Transformation of Vesicles Studied by Ferritin Labeling and Cryotransmission Electron Microscopy. J. Phys. Chem. B 105, 1056–1064 (2001a)
Bloechliger, E., Blocher, M., Walde, P., Luisi, P.L.: Matrix Effect in the Size Distribution of Fatty Acid Vesicles. J. Phys. Chem. 102, 10383–10390 (1998)
Chen, I.A., Roberts, R.W., Szostak, J.W.: The Emergence of Competition Between Model Protocells. Science 305, 1474–1476 (2004)
Chen, I.A., Szostak, J.W.: A Kinetic Study of the Growth of Fatty Acid Vesicles. Biophys. J. 87, 988–998 (2004a)
Chen, I.A., Szostak, J.W.: Membrane growth can generate a transmembrane pH gradient in fatty acid vesicle. Proc. Nat. Ac. Sci. USA 101(21), 7965–7970 (2004b)
Cheng, Z., Luisi, P.L.: Coexistence and mutual competion of vesicles with different size distributions. J. Phys. Chem. B 107(39), 10940–10945 (2003)
Deamer, D.W.: Origins of life: how leaky were primitive cells? Nature 454, 37–38 (2008)
de Duve, C.: Blueprint for a cell: the nature and origin of life. Neil Patterson Publishers, Burlington (1991)
Eigen, M., Winkler-Oswatitsch, R.: Steps towards life: A perspective on evolution. Oxford Univ. Press, New York (1992)
Ganti, T.: On the early evolutionary origin of biological periodicity. Cell Biol. Int. 26, 729–735 (2002)
Gillespie, D.T.: A General Method for Numerically Simulating the Stochastic Time Evolution of Coupled Chemical Reactions. J. Comput. Phys. 22, 403–434 (1976)
Gillespie, D.T.: Exact Stochastic Simulation of Coupled Chemical Reactions. J. Phys. Chem. 81, 2340–2369 (1977)
Hanczyc, M.M., Fujikawa, S.M., Szostak, J.W.: Experimental Models of Primitive Cellular Compartments: Encapsulation, Growth, and Division. Science 302, 618–621 (2003)
Kauffman, S.: The origins of order: Self-organization and selection in evolution. Oxford Univ. Press, Oxford (1993)
Mansy, S., et al.: Template directed synthesis of a genetic polymer in a model protocell. Nature 454, 122–126 (2008)
Mavelli, F., Ruiz-Mirazo, K.: Stochastic simulations of minimal self-reproducing cellular systems. Phil. Trans. Royal. Society of London B 362(1486), 1789–1802 (2007)
Mavelli, F., Lerario, M., Ruiz-Mirazo, K.: ‘ENVIRONMENT’: a stochastic simulation platform to study protocell dynamics. In: Arabnia, H.R., et al. (eds.) Proceedings of BIOCOMP 2008, vol. II, pp. 934–941. CSREA Press (2008)
Monnard, P.-A., Deamer, D.W.: Nutrient uptake by protocells: a liposome model system. Origins of Life and Evolution of the Biosphere 31, 147–155 (2001)
Monnard, P.-A., Deamer, D.W.: Membrane Self-Assembly Processes: Steps Toward the First Cellular Life. Anat. Rec. 268, 196–207 (2002)
Morigaki, K., Walde, P.: Fatty acid vesicles. Cur. Opin. Coll. & Interface Science 12, 75–80 (2007)
Ourisson, G., Nakatani, Y.: The terpenoid theory of the origin of cellular life: the evolution of terpenoids to cholesterol. Chem. & Biol. 1, 11–23 (1994)
Peretó, J., et al.: Ancestral lipid biosynthesis and early membrane evolution. TIBS 29(9), 469–477 (2004)
Ruiz-Mirazo, K., Moreno, A.: Basic autonomy as a fundamental step in the synthesis of life. Artificial Life 10(3), 235–259 (2004)
Ruiz-Mirazo, K., Mavelli, F.: Simulation Model for Functionalized Vesicles: Lipid-Peptide Integration in Minimal Protocells. In: Almeida e Costa, F., Rocha, L.M., Costa, E., Harvey, I., Coutinho, A. (eds.) ECAL 2007. LNCS (LNAI), vol. 4648, pp. 32–41. Springer, Heidelberg (2007)
Ruiz-Mirazo, K., Mavelli, F.: On the way towards ‘basic autonomous agents’: stochastic simulations of minimal lipid-peptide cells. BioSystems 91, 374–387 (2008)
Varela, F.J., Maturana, H., Uribe, R.: Autopoiesis: The Organization of Living Systems, its characterization and a model. BioSystems 5, 187–196 (1974)
Walde, P., Wick, R., Fresta, M., Mangone, M., Luisi, P.L.: Autopoietic Self-Reproduction of Fatty Acid Vesicles. J. Am. Chem. Soc. 116, 11649–11654 (1994)
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Piedrafita, G., Mavelli, F., Morán, F., Ruiz-Mirazo, K. (2011). On the Transition from Prebiotic to Proto-biological Membranes: From ‘Self-assembly’ to ‘Self-production’. In: Kampis, G., Karsai, I., Szathmáry, E. (eds) Advances in Artificial Life. Darwin Meets von Neumann. ECAL 2009. Lecture Notes in Computer Science(), vol 5777. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-21283-3_32
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DOI: https://doi.org/10.1007/978-3-642-21283-3_32
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