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Effect of Sulfur Dioxide Sub-chronic Exposure on Cytokine Levels in Lungs and Serum of Rats

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Advances in Computer Science, Intelligent System and Environment

Part of the book series: Advances in Intelligent and Soft Computing ((AINSC,volume 106))

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Abstract

Both male and female rats were exposed to SO2 while their controls were exposed to filtered air. Levels of interlukin-6 (IL-6), tumor necrosis factor-α (TNF-α), transforming growth factor- β1 (TGF- β1) in rat lung and serum were measured by the enzyme-linked immunosorbent assay (ELISA) after chronic exposure to SO2. A statistically significant increase in the levels of IL-6 and TNF-α was observed in the lung tissues of both male and female rats. No effects on tested cytokines were observed in rat serum, except for a significant increase in TNF-α level in male rats. There is no significant change in TGF- β1 level in rat lung and serum.

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Li, F., Liu, Y. (2011). Effect of Sulfur Dioxide Sub-chronic Exposure on Cytokine Levels in Lungs and Serum of Rats. In: Jin, D., Lin, S. (eds) Advances in Computer Science, Intelligent System and Environment. Advances in Intelligent and Soft Computing, vol 106. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-23753-9_19

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  • DOI: https://doi.org/10.1007/978-3-642-23753-9_19

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-23752-2

  • Online ISBN: 978-3-642-23753-9

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