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Toward Elucidation of Longevity of Immunological Memory

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Book cover Knowledge-Based and Intelligent Information and Engineering Systems (KES 2011)

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 6884))

Abstract

An interesting and substantial feature of the immune memory is its eventual loss, namely “longevity”. An extension of longevity is a significant issue for efficacy of vaccines. We have discussed possible mechanisms of an immune memory with longevity from a dynamical viewpoint, and demonstrated that a particular transient dynamics was promising for reproducing an immune memory with longevity. The present paper analytically derives an equation to estimate the longevity and clarifies a dependency relationship between system parameters and longevity of an immune memory. Finally it confirms validity of the relationship from an immunological viewpoint.

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Author information

Authors and Affiliations

  1. Toyohasi University of Technology, 1-1, Tenpaku, Toyohashi-shi, Aichi, 441-8585, Japan

    Kouji Harada & Yoshiteru Ishida

Authors
  1. Kouji Harada
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  2. Yoshiteru Ishida
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Editor information

Editors and Affiliations

  1. Institute of Integrated Sensor Systems, University of Kaiserslautern, Erwin-Schroedinger-str. 12, 67663, Kaiserslautern, Germany

    Andreas König

  2. Knowledge-Based Systems Group, Department of Computer Science, University of Kaiserslautern, P.O. Box 3049, 67653, Kaiserslautern, Germany

    Andreas Dengel

  3. School of Business, University of Applied Sciences Northwestern Switzerland, Riggenbachstr. 16, 4600, Olten, Switzerland

    Knut Hinkelmann

  4. Graduate School of Engineering, Osaka Prefecture University, 1-1 Gakuen-cho, 599-8531, Sakai, Osaka, Japan

    Koichi Kise

  5. KES International, P.O. Box 2115, BN43 9AF, Shoreham-by-sea, UK

    Robert J. Howlett

  6. University of South Australia, Adelaide, 5095, Mawson Lakes, SA, Australia

    Lakhmi C. Jain

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© 2011 Springer-Verlag Berlin Heidelberg

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Harada, K., Ishida, Y. (2011). Toward Elucidation of Longevity of Immunological Memory. In: König, A., Dengel, A., Hinkelmann, K., Kise, K., Howlett, R.J., Jain, L.C. (eds) Knowledge-Based and Intelligent Information and Engineering Systems. KES 2011. Lecture Notes in Computer Science(), vol 6884. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-23866-6_33

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  • DOI: https://doi.org/10.1007/978-3-642-23866-6_33

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-23865-9

  • Online ISBN: 978-3-642-23866-6

  • eBook Packages: Computer ScienceComputer Science (R0)

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