Abstract
Objective: 16-channel EEG data during intermittent episodes of epilepsy is recoded and analyzed to find lesions source and relationship between brain areas for temporal lobe epilepsy (TLE) patients by causal analysis method.
Methods: There are 8 patients with temporal lobe epilepsy, 5 males and 3 females, aged between 19 to 47 years, the average age of 30.63 years. 16-channel EEG in 8 patients was recorded by Stellate Video EEG. Sample time = 20s (sample points = 4000), Sampling frequency f s = 2 0 0 H z. Directional transfer functions is used to direct the information transduction between each channel of the EEG signals, which can reflect the causal relationship between each channel and determine the location of the lesions source. (In this paper, we used eConnectome software that developed by Biomedical Functional Imaging and Neuroengineering Laboratory at the University of Minnesota, directed by Dr. Bin He).
Results: Causality results of 8 patients during intermittent episodes of EEG 20s are as follows: 6 patients’ lesions source are located on channels T5 and F7 in left tempora, One of 5 cases’ are located on channel T5 in the left posterior temporal, One of 1 case is located on channel F7 in the left anterior temporal. And 2 patients’ lesions source are located on channels T4 and T6 in the right tempora, in the 2 patients, 1 case’s lesions source is located on channel T4 in right middle temporal, 1 case’s lesions source is located on channel T6 in right posterior temporal. Causality results consistent with the clinical diagnosis.
Conclusions: Research of EEG on causal analysis of directional transfer function can effectively determine the lesions source of seizure, and effectively calculate the transmission direction of the multi-channel information, which is to provide support in the clinic for determine the source of seizure.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Marinazzo, D., Liao, W., Chen, H., Stramaglia, S.: Nonlinear connectivity by Granger causality. Neurolmage 99, 9–18 (2010)
Astolfi, L., Cincotti, F., Mattia, D., Babilonic, C., Carducci, F., Basilisco, A., Rossini, P.M., Salinari, S., Ding, L., Ni, Y., He, B., Babiloni, F.: Assessing cortical functional connectivity by linear inverse estimation and directed transfer function. Simulations and Application to Real Data Clinical Neurophysiology 116, 920–932 (2005)
Londei, A., D’Ausilio, A., Basso, D., et al.: Brain network for passive word listening as evaluated with ICA and Granger causality. Brain Research Bulletin 72, 284–292 (2007)
Babiloni, F., Cincotti, F., Babiloni, C., Carducci, F., Mattia, D., Astolfi, L., Basilisco, A., Rossini, P.M., Ding, L., Ni, Y., Cheng, J., Christine, K., Sweeney, J., He, B.: Estimation of the cortical functional connectivity with the multimodal integration of high-resolution EEG and fMRI data by directed transfer function. Neuroimage 24(1), 118–131 (2005)
Anna, K.: Determination of information flow direction among brain structures by a modified directed transfer function (dDTF) method. Journal of Neuroscience Methods 125, 195–207 (2003)
Franaszczuk, P.J., Bergey, G.K.: Application of the Directed Transfer Function Method to Mesial and Lateral Onset Temporal Lobe Seizures. Brain Topography, 11–12 (1998)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2011 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Qiu, ZJ., Zhang, HY., Tian, X. (2011). Research of EEG from Patients with Temporal Lobe Epilepsy on Causal Analysis of Directional Transfer Functions. In: Lu, BL., Zhang, L., Kwok, J. (eds) Neural Information Processing. ICONIP 2011. Lecture Notes in Computer Science, vol 7062. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-24955-6_41
Download citation
DOI: https://doi.org/10.1007/978-3-642-24955-6_41
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-24954-9
Online ISBN: 978-3-642-24955-6
eBook Packages: Computer ScienceComputer Science (R0)