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Volume-Rendering of Mitochondrial Transports Using VTK

  • Conference paper
Software Engineering, Business Continuity, and Education (ASEA 2011)

Part of the book series: Communications in Computer and Information Science ((CCIS,volume 257))

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Abstract

Mitochondria is an important organelle for maintaining cells such as neurons’ physiological processes. Mitochondrial transport is known to be strongly related to neurodegenerative disease of the central nervous system such as Alzheimer’s disease and Parkinson’s disease. Recently a novel micro-fluidic culture platform enabled in-vivo mitochondrial being imaged using a confocal microscope. However, automated analysis of these images is still infeasible because of the low signal-to-noise ratio and formidable amount of image data. Noticing that three dimensional (3-D) visualization techniques have been useful to handle these limitations, we develop a volume-rendering tool using the Visualization Toolkit (VTK), which facilitates analysis of mitochondrial transports and comprehension of the correlations with characteristics of neurons.

This research was supported by Basic Science Research Program through the National Research Foundation (NRF) funded by the Ministry of Education, Science, and Technology (2009-0069549).

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References

  1. Malaiyan, L.M., Honick, A.S., Rintoul, G.L., Wang, Q.J., Reynolds, I.J.: Zn2+ inhibits mitochondrial movement in neurons by phosphatidylinositol 3-Kinase activation. Journal of Neuroscience 25(41), 9507–9514 (2005)

    Article  Google Scholar 

  2. Cheng, D.T.W., Honick, A.S., Reynolds, I.J.: Mitochondrial trafficking to synapses in cultured primary cortical neurons. Journal of Neuroscience 26, 7035–7045 (2006)

    Article  Google Scholar 

  3. Reynolds, I.J., Santos, S.: Rotenone inhibits movement and alters morphology of mitochondria in culture forebrain neurons. Society Neuroscience Abstract 31, 1017–1019 (2005)

    Google Scholar 

  4. Taylor, A.M., Blurton-Jones, M., Rhee, S.W., Cribbs, D.H., Cotman, C.W., Jeon, N.L.: A Microfluidic Culture Platform for CNS Axonal Injury, Regeneration and Transport. Nature Methods 2(8) (August 2005)

    Google Scholar 

  5. Miller, K.E., Sheetz, M.P.: Axonal mitochondrial transport and potential are correlated. Journal of Cell Science 117, 2791–2804 (2004)

    Article  Google Scholar 

  6. Kitware, Inc., The VTK User’s Guide: Updated for VTK 4.4, Kitware, Inc. (2004)

    Google Scholar 

  7. Park, J.W., Vahidi, B., Taylor, A.M., Rhee, S.W., Jeon, N.L.: Microfluidic culture platform for neuroscience research. Nature Protocols 1(4), 2128–2136 (2006)

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Computer Science and Engineering, Hankuk University of Foreign Studies, Kyonggi, 449-791, Republic of Korea

    Yeonggul Jang & Yoojin Chung

  2. Cardiovascular Research Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, Republic of Korea

    Hackjoon Shim

Authors
  1. Yeonggul Jang
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  2. Hackjoon Shim
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  3. Yoojin Chung
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Editor information

Editors and Affiliations

  1. Multimedia Engineering Department, Hannam University, 133 Ojeong-dong, Daeduk-gu, Daejeon, Korea

    Tai-hoon Kim

  2. The Ohio State University, 470 Hitchcock Hall, 2070 Neil Avenue, 43210-1275, Columbus, OH, USA

    Hojjat Adeli

  3. Catholic University of Daegu, South Korea

    Haeng-kon Kim

  4. Dept. of Computer Engineering, Mokwon University, 800, Doan-dong, Seo-gu, 302-729, Daejeon, Korea

    Heau-jo Kang

  5. Woosuk University, 565-701, Jeollabuk-do, Korea

    Kyung Jung Kim

  6. University of Michigan-Dearborn, Dearborn, MI, USA

    Akingbehin Kiumi

  7. School of Computing and Information Systems, University of Tasmania, Hobart, TAS, Australia

    Byeong-Ho Kang

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© 2011 Springer-Verlag Berlin Heidelberg

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Jang, Y., Shim, H., Chung, Y. (2011). Volume-Rendering of Mitochondrial Transports Using VTK. In: Kim, Th., et al. Software Engineering, Business Continuity, and Education. ASEA 2011. Communications in Computer and Information Science, vol 257. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27207-3_7

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  • DOI: https://doi.org/10.1007/978-3-642-27207-3_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-27206-6

  • Online ISBN: 978-3-642-27207-3

  • eBook Packages: Computer ScienceComputer Science (R0)

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