Abstract
CEDM is a radiological technique based on the use of digital mammography equipment and the injection of an iodinated contrast medium to enhance the visualization of tissues of interest. In previous works, our group has proposed a formalism for the use of dual-energy temporal CEDM, based on weighted subtraction of images, that has been applied with success to phantom data. This methodology requires the selection of ROIs by a radiologist, to determine the weight factors. In this work, we propose an alternative that improves the contrast in clinical images resulting from dual-energy temporal CEDM subtraction, while freeing the method from ambiguities due to the ROI selection by a radiologist. The new subtraction algorithm is based on the use of weight factors calculated pixel-by-pixel. The main result after evaluation of the methodology on images of 10 patients randomly chosen is a substantial improvement of the contrast (~5 times), reaching values that are similar to those obtained with single energy subtraction.
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References
Yaffe, M.J.: Advanced Applications of Digital Mammography. In: Pisano, E.D., Yaffe, M.J., Kuzmiak, C.M. (eds.) Digital Mammography, pp. 67–76. Lippincott Williams & Wilkins, Philadelphia (2004)
Dromain, C., Balleyguier, C., Adler, G., Garbay, J.R., Delaloge, S.: Contrast-Enhanced Digital Mammography. Eur. J. Radiol. 69(1), 34–42 (2009)
Dromain, C., Balleyguier, C., Muller, S., Mathieu, M.C., Rochard, F., Opolon, P., Sigal, R.: Evaluation of Tumor Angiogenesis of Breast Carcinoma Using Contrast-Enhanced Digital Mammography. Am. J. Roentgenol. 187(5), W528–W537 (2006)
Boone, J.M., Shaber, G.S., Tecotzky, M.: Dual-Energy Mammography: a Detector Analysis. Med. Phys. 17(4), 665–675 (1990)
Rosado-Méndez, I., Palma, B.A., Brandan, M.E.: Analytical Optimization of Digital Subtraction Mammography with Contrast Medium Using a Commercial Unit. Med. Phys. 35(12), 5544–5557 (2008)
Palma, B.A., Rosado-Méndez, I., Villaseñor, Y., Brandan, M.E.: Phantom Study to Evaluate Contrast-Medium-Enhanced Digital Subtraction Mammography with a Full-Field Indirect-Detection System. Med. Phys. 37(2), 577–589 (2009)
Highnam, R., Brady, M., Shepstone, B.: A Representation for Mammographic Image Processing. Medical Image Analysis 1(1), 1–18 (1996)
Lemacks, M.R., Kappadath, S.C., Shaw, C.C., Liu, X., Whitman, G.J.: A Dual-Energy Subtraction Technique for Microcalcification Imaging in Digital Mammography–A Signal-to-Noise Analysis. Med. Phys. 29(8), 1739–1751 (2002)
Boone, J.M., Fewell, T.R., Jennings, R.J.: Molybdenum, Rhodium, and Tungsten Anode Spectral Models Using Interpolating Polynomials with Application to Mammography. Med. Phys. 24(12), 1863–1874 (1997)
Schaefer, S., McPhail, T., Warren, J.: Image Deformation Using Moving Least Squares. ACM Transactions on Graphics 25(3), 533–540 (2006)
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Cruz-Bastida, JP. et al. (2012). Contrast Optimization in Clinical Contrast-Enhanced Digital Mammography Images. In: Maidment, A.D.A., Bakic, P.R., Gavenonis, S. (eds) Breast Imaging. IWDM 2012. Lecture Notes in Computer Science, vol 7361. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-31271-7_3
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DOI: https://doi.org/10.1007/978-3-642-31271-7_3
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