Abstract
In defense and security, there is a need to develop more sensitive and selective sensors to allow the detection of toxic and illicit compounds at trace levels. Photonic Integrated Circuits combined with specific protein bio-recognition allowed us to detect DMMP vapors down to 20 ppb in the gas phase. This strong increase in sensitivity results from the specific binding of DMMP molecules in the protein cavity. A high coverage ratio of the ring resonator with proteins permits the enhancement of the wave propagation signal resulting from the adsorption of one DMMP molecule on each biosensing protein, resulting in an amplified optical signal.
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References
Narayanaswamy, R., Wolfbeis, O.: Optical sensors. Springer, New York (2004)
Jokerst, N., Royal, M., Palit, S., Luan, L., Dhar, S., Tyler, T.J.: Biophoton 2, 212–226 (2009)
Bañuls, M.J., González-Pedro, V., Barrios, C.A., Puchades, R., Maquieira, A.: Biosens. Bioelectron 25, 1460–1466 (2010)
Moerner, W.: Proc. Nat. Acad. Sci. U.S.A. 104, 12596–12602 (2007)
Claes, T., Bogaerts, W., Bientsman, P.: Optics Express 18, 22747–22761 (2010)
Barrios, C., Gylfason, K., Sanchez, B., Griol, A., Sohlström, H., Holgado, M., Casquel, R.: Opt. Lett. 32, 3080–3082 (2007)
Orghici, R., Lützow, P., Burgmeier, J., Koch, J., Heidrich, H., Schade, W., Welschoff, N., Waldvogel, S.: Sensors 10, 6788–6795 (2010)
Hou, C., Yang, L., Huo, D.: Spectrophotometric detection of dimethyl methyl-phosphonate using plant-esterase. In: The 2nd International Conference on Bioinformatics and Biomedical Engineering, ICBBE 2008, pp. 1640–1643. IEEE (2008)
Grate, J., Rose-Pehrsson, S., Venezky, D., Klusty, M., Wohltjen, H.: Anal. Chem. 65, 1868–1881 (1993)
Zimmermann, C., Mazein, P., Rebiere, D., Dejous, C., Pistre, J., Planade, R.: IEEE Sensors Journal 4, 479–488 (2004)
Wang, F., Gu, H., Swager, T.J.: Am. Chem. Soc. 130, 5392–5393 (2008)
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Bonnot, K. et al. (2012). A Biophotonic Sensor for the Specific Detection of DMMP Vapors at the ppb Level. In: Aschenbruck, N., Martini, P., Meier, M., Tölle, J. (eds) Future Security. Future Security 2012. Communications in Computer and Information Science, vol 318. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-33161-9_60
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DOI: https://doi.org/10.1007/978-3-642-33161-9_60
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-33160-2
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