Abstract
Genetic Algorithms (GAs) is one of the most effective technique applied to feature selection in medical diagnostic decisions. In particular, Thalassemia, which is one of the most common genetic disorders found around the world. The main problems of diagnosing this disease are the complex processes for identifying the several types of Thalassemia. Moreover, diagnostic methods are slow and rely on expert knowledge and experience as well as expensive equipment. For these reasons, in this study, a new framework of applied DBN and BLR (MCMC)-GAs-KNN for Thalassemia Expert System is proposed. The filter techniques called DBNs and the hybrid classification technique namely BLR (MCMC)-GAs-KNN will be used for classifying the types of β-Thalassemia. The obtained result will be compared to the results of other techniques such as BNs, BLR based on Classical (ML) and Bayesian (MCMC) approach, SVM, MLP, KNN, C5.0, and CART for selecting the best results to implement Thalassemia Expert System.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Elami, M.E.: A Filter Model for Feature Subset Selection Based on Genetic Algorithm. Journal of Knowledge-Based Systems 22, 356–362 (2009)
Yannis, M., Georgios, D., Jan, J.: Pap Smear Diagnosis Using a Hybrid Intelligent Scheme Focusing on Genetic Algorithm Based Feature Selection and Nearest Neighbor Classification. Journal of Computers in Biology and Medicine 39, 69–78 (2009)
Jin-Hyuk, H., Sung-Bae, C.: Efficient Huge-scale Feature Selection with Speciated Genetic Algorithm. Journal of Pattern Recognition Letters 27, 143–150 (2006)
Zexuan, Z., Yew, S., Manoranjan, D.: Markov Blanket-embedded Genetic Algorithm for Gene Selection. Pattern Recognition 40, 3236–3248 (2007)
Patcharaporn, P., Michele, C., Somdet, S.: The Effeciency of Data Types for Classification Performance of Machine Learning Techniques for Screening β-Thalassemia. In: 3rd International Symposium on Applied Sciences in Biomedical and Communication Technologies, pp. 1–4. IEEE Press, New York (2010)
Patcharaporn, P., Napat, H., Nopasit, C., Michelle, C., Somdet, S.: Parameter Estimation of Binomial Logistic Regression Based on Classical (Maximum Likelihood) and Bayesian (MCMC) Approach for Screening β-Thalassemia. International Journal of Intelligent Information Processing 3, 90–100 (2012)
Patcharaporn, P., Napat, H.: Risk Analysis of Thalassemia Using Knowledge Representation Model: Diagnostic Bayesian networks. In: International Conference on Biomedical and Health Informatics, pp. 155–158. IEEE Press, New York (2012)
Te-Sheng, L.: Feature Selection for Classification By Using A GA-Based Neural Network Approach. Journal of the Chinese Institute of Industrial Engineers 23, 55–64 (2006)
Sihua, P., Qianghua, X., Xuefeng, B.L., Xiaoning, P., Wei, D., Liangbiao, C.: Molecular Classification of Cancer Types from Microarray Data Using the Combination of Genetic Algorithms and Support Vector Machines. FEBS Letters 555, 358–362 (2003)
Wu, X., Kumar, V., Quinlan, J.R., Ghosh, J., Yang, Q., Motoda, H.: Top 10 Algorithms in Data Mining. Journal of Knowledge Information System 14, 1–37 (2008)
Patcharaporn, P., Napat, H., Nopasit, C.: The Classification Performance of Binomial Logistic Regression Based on Classical and Bayesian Statistics for Screening β-Thalassemia. In: 3rd International Conference on Data Mining and Intelligent Information Technology Applications, pp. 427–432 (2011)
Patcharaporn, P., Michele, C., Napat, H., Nopasit, C., Somdet, S.: Rule Induction for Screening Thalassemia Using Machine Learning Techniques: C5. 0 and CART. ICIC Express Letter 6, 301–306 (2012)
Patcharaporn, P., Michele, C., Napat, H., Somdet, S.: The Comparison of Classification Performance of Machine Learning Techniques Using Principal Components Analysis: PCA for Screening β-Thalassemia. In: 4th International Conference on Computer Science and Information Technology, pp. 316–319 (2011)
Patcharaporn, P.: Reasoning Matrices and Polychomatic Set for Screening Thalassemia. Journal of Medical Research and Science 2, 144–152 (2012)
Patcharaporn, P.: Knowledge and Data Engineering: Fuzzy C-Mean and Genetic Algorithms for Clustering?-Thalassemia of Knowledge Based Diagnosis Decision Support System. ICIC Express Letter (in Press, 2012)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2012 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Paokanta, P. (2012). DBNs-BLR (MCMC) -GAs-KNN: A Novel Framework of Hybrid System for Thalassemia Expert System. In: Huang, T., Zeng, Z., Li, C., Leung, C.S. (eds) Neural Information Processing. ICONIP 2012. Lecture Notes in Computer Science, vol 7666. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-34478-7_33
Download citation
DOI: https://doi.org/10.1007/978-3-642-34478-7_33
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-34477-0
Online ISBN: 978-3-642-34478-7
eBook Packages: Computer ScienceComputer Science (R0)