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Data Reconciliation of Release Mechanism Research of LDH-Based Drug

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Advances in Swarm Intelligence (ICSI 2013)

Part of the book series: Lecture Notes in Computer Science ((LNTCS,volume 7929))

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Abstract

Sebacate pillared layered double hydroxides (LDH) was prepared via co-precipitation method. And then the drug 10-hydroxy-camptothecin (10-HC) was intercalated into the gallery of LDH to form the drug–LDH composites. Three types of dissolution- diffusion kinetics models were used to make clear the drug release mechanism of the LDH composites. For the first time data reconciliation was used to make clear the drug release kinetics mechanism of the LDH composites, which was carried out by using a data filter algorithm based on first-order delay filter and time-delay principle to diminish random experimental errors resulting from the factors including stirring speed, solid content, and so on. Simulation results indicated that the data reconciliation adequately degraded the interactions between drug release rates at different times and made the data satisfy the kinetics models for the drug release mechanism more accurately.

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Author information

Authors and Affiliations

  1. Information Technology Department of Qingdao Vocational & Technical College of Hotel Management, Qingdao, Shandong, China, 266100

    Xiaoxia Liu

Authors
  1. Xiaoxia Liu
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Editors and Affiliations

  1. Key Laboratory of Machine Perception (MOE), School of lectronics Engineering and Computer Science, Department of Machine Intelligence, Peking University, 100871, Beijing, China

    Ying Tan

  2. Department of Electrical and Electronic Engineering, Xi’an Jiaotong-Liverpool University, 215123, Suzhou, China

    Yuhui Shi

  3. Automation College, Harbin Engineering University, 150001, Harbin, China

    Hongwei Mo

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Liu, X. (2013). Data Reconciliation of Release Mechanism Research of LDH-Based Drug. In: Tan, Y., Shi, Y., Mo, H. (eds) Advances in Swarm Intelligence. ICSI 2013. Lecture Notes in Computer Science, vol 7929. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38715-9_63

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  • DOI: https://doi.org/10.1007/978-3-642-38715-9_63

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-38714-2

  • Online ISBN: 978-3-642-38715-9

  • eBook Packages: Computer ScienceComputer Science (R0)

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