Skip to main content

Multi-Agent, Multi-Case-Based Reasoning

  • Conference paper
Case-Based Reasoning Research and Development (ICCBR 2013)

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 7969))

Included in the following conference series:

Abstract

A new paradigm for case-based reasoning described here assembles a set of cases similar to a new case, solicits the opinions of multiple agents on them, and then combines their output to predict for a new case. We describe the general approach, along with lessons learned and issues identified. One application of the paradigm schedules constraint satisfaction solvers for parallel processing, based on their previous performance in competition, and produces schedules with performance close to that of an oracle. A second application predicts protein-ligand binding, based on an extensive chemical knowledge base and three sophisticated predictors. Despite noisy, biased biological data, the paradigm outperforms its constituent agents on benchmark protein-ligand data, and thereby promises faster, less costly drug discovery.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Dietterich, T.G.: Ensemble methods in machine learning. In: Kittler, J., Roli, F. (eds.) MCS 2000. LNCS, vol. 1857, pp. 1–15. Springer, Heidelberg (2000)

    Chapter  Google Scholar 

  2. Leake, D.B., Sooriamurthi, R.: Automatically Selecting Strategies for Multi-Case-Base Reasoning. In: Craw, S., Preece, A.D. (eds.) ECCBR 2002. LNCS (LNAI), vol. 2416, pp. 204–233. Springer, Heidelberg (2002)

    Chapter  Google Scholar 

  3. Plaza, E., McGinty, L.: Distributed Case-Based Reasoning. The Knowledge Engineering Review 20(3), 261–265 (2005)

    Article  Google Scholar 

  4. Redmond, M.: Distributed Cases for Case-Based Reasoning: Facilitating Use of Multiple Cases. In: Proceedings of the Eighth National Conference on Artificial Intelligence (AAAI 1990), pp. 304–309 (1990)

    Google Scholar 

  5. Kar, D., Chakraborti, S., Ravindran, B.: Feature Weighting and Confidence Based Prediction for Case Based Reasoning Systems. In: Agudo, B.D., Watson, I. (eds.) ICCBR 2012. LNCS, vol. 7466, pp. 211–225. Springer, Heidelberg (2012)

    Chapter  Google Scholar 

  6. Yun, X., Epstein, S.L.: Learning Algorithm Portfolios for Parallel Execution. In: Hamadi, Y., Schoenauer, M. (eds.) LION 2012. LNCS, vol. 7219, pp. 323–338. Springer, Heidelberg (2012)

    Chapter  Google Scholar 

  7. Guerri, A., Milano, M.: Learning Techniques for Automatic Algorithm Portfolio Selection. In: Proceedings of the Sixteenth European Conference on Artificial Intelligence, pp. 475–479 (2004)

    Google Scholar 

  8. O’Mahony, E., Hebrard, E., Holland, A., Nugent, C., O’Sullivan, B.: Using Case-Based Reasoning in an Algorithm Portfolio for Constraint Solving. In: Proceedings of the Nineteenth Irish Conference on Artificial Intelligence and Cognitive Science (2008)

    Google Scholar 

  9. Silverthorn, B., Miikkulainen, R.: Latent Class Models for Algorithm Portfolio Methods. In: Proceedings of the Twenty-Fourth AAAI Conference on Artificial Intelligence, pp. 167–172 (2010)

    Google Scholar 

  10. Xu, L., Hoos, H.H., Leyton-Brown, K.: Hydra: Automatically Configuring Algorithms for Portfolio-Based Selection. In: Proceedings of the Twenty-Fourth AAAI Conference on Artificial Intelligence, pp. 210–216 (2010)

    Google Scholar 

  11. Xu, L., Hutter, F., Hoos, H.H., Leyton-Brown, K.: SATzilla: Portfolio-Based Algorithm Selection for SAT. Journal of Artificial Intelligence Research 32, 565–606 (2008)

    MATH  Google Scholar 

  12. Horvitz, E., Ruan, Y., Gomes, C.P., Kautz, H.A., Selman, B., Chickering, D.M.: A Bayesian Approach to Tackling Hard Computational Problems. In: Proceedings of the Seventeenth Conference in Uncertainty in Artificial Intelligence, pp. 235–244. Morgan Kaufmann Publishers Inc. (2001)

    Google Scholar 

  13. Streeter, M., Golovin, D., Smith, S.F.: Combing Multiple Heuristics Online. In: Proceedings of the Twenty-Second National Conference on Artificial Intelligence, pp. 1197–1203 (2007)

    Google Scholar 

  14. Mistral, http://4c.ucc.ie/~ehebrard/Software.html

  15. Third International CSP Solver Competition (CPAI 2008), http://www.cril.univ-artois.fr/CPAI08/

  16. Fourth International CSP Solver Competition (CSC 2009), http://www.cril.univ-artois.fr/CSC09/

  17. Huang, S.-Y., Zou, X.: Advances and Challenges in Protein-Ligand Docking. International Journal of Molecular Science 11, 3016–3034 (2010)

    Article  Google Scholar 

  18. Charifson, P.S., Corkery, J.J., Murcko, M.A., Walters, W.P.: Consensus Scoring: A Method for Obtaining Improved Hit Rates from Docking Databases of Three-Dimensional Structures into Proteins. Journal of Medicinal Chemistry 42, 5100–5109 (1999)

    Article  Google Scholar 

  19. Clark, R.D., Strizhev, A., Leonard, J.M., Blake, J.F., Matthew, J.B.: Consensus Scoring for Ligand/Protein Interactions. Journal of Molecular Graphics Modelling 20, 281–295 (2002)

    Article  Google Scholar 

  20. Wang, R., Wang, S.: How Does Consensus Scoring Work for Virtual Library Screening? An Idealized Computer Experiment. Journal of Chemical Information and Computer Sciences 41, 1422–1426 (2001)

    Google Scholar 

  21. Zsoldos, Z., Reid, D., Simon, A., Sadjad, B.S., Johnson, P.A.: Ehits: An Innovative Approach to the Docking and Scoring Function Problems. Current Protein and Peptide Science 7, 421–435 (2006)

    Article  Google Scholar 

  22. Trott, O., Olson, A.J.: Autodock Vina: Improving the Speed and Accuracy of Docking with a New Scoring Function, Efficient Optimization and Multithreading. Journal of Computational Chemistry 31, 455–461 (2010)

    Google Scholar 

  23. Morris, G.M., Goodsell, D.S., Halliday, R.S., Huey, R., Hart, W.E., Belew, R.K., Olson, A.J.: Automated Docking Using a Lamarckian Genetic Algorithm and Empirical Binding Free Energy Function. Journal of Computational Chemistry 19, 1639–1662 (1998)

    Article  Google Scholar 

  24. Miteva, M.A., Lee, W.H., Montes, M.O., Villoutreix, B.O.: Fast Structure-Based Virtual Ligand Screening Combining Fred, Dock, and Surflex. Journal of Medicinal Chemistry 48, 6012–6022 (2005)

    Article  Google Scholar 

  25. Fukunishi, H., Teramoto, R., Takada, T., Shimada, J.: Bootstrap-Based Consensus Scoring Method for Protein-Ligand Docking. Journal of Chemical Information and Modeling 48, 988–996 (2008)

    Article  Google Scholar 

  26. Huang, N., Shoichet, B.K., Irwin, J.J.: Benchmarking Sets for Molecular Docking. Journal of Medicinal Chemistry 49, 6789–6801 (2006)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Epstein, S.L., Yun, X., Xie, L. (2013). Multi-Agent, Multi-Case-Based Reasoning. In: Delany, S.J., Ontañón, S. (eds) Case-Based Reasoning Research and Development. ICCBR 2013. Lecture Notes in Computer Science(), vol 7969. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-39056-2_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-39056-2_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-39055-5

  • Online ISBN: 978-3-642-39056-2

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics