Abstract
Early detection of risk of breast cancer is of upmost importance for effective treatment. In the field of medical image analysis, automatic methods have been developed to discover features of ductal trees that are correlated with radiological findings regarding breast cancer. In this study, a data mining approach is proposed that captures a new set of geometrical properties of ductal trees. The extracted features are employed in an ensemble learning scheme in order to classify galactograms, medical images which visualize the tree structure of breast ducts. For classification, three variants of the AdaBoost algorithm are explored using as weak learner the CART decision tree. Although the new methodology does not improve the classification performance compared to state-of-the-art techniques, it offers useful information regarding the geometrical features that could be used as biomarkers providing insight to the relationship between ductal tree topology and pathology of human breast.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Guray, M., Sahin, A.A.: Benign Breast Diseases: Classification, Diagnosis, and Management. The Oncologist 11(5), 435–449 (2006)
Eyal, E., Furman-Haran, E., Degani, H.: 3-D tracking of the mammary ductal tree using diffusion tensor MR imaging. In: Proceedings of International Society for Magnetic Resonance in Medicine (ISMRM), pp. 588–590 (2008)
Skoura, A., Barnathan, M., Megalooikonomou, V.: Classification of ductal tree structures in galactograms. In: Proceedings of 6th IEEE Int. Symposium on Biomedical Imaging (ISBI), pp. 1015–1018. IEEE Press (2009)
Megalooikonomou, V., Barnathan, M., Kontos, D., Bakic, P.R., Maidment, A.D.: A Representation and Classification Scheme for Tree-like Structures in Medical Images: Analyzing the Branching Pattern of Ductal Trees in X-ray Galactograms. IEEE Trans. on Medical Imaging 28(4), 487–493 (2009)
Bakic, P.R., Albert, M., Maidment, A.D.: Classification of galactograms with ramification matrices: preliminary results. Academic Radiology 10, 198–204 (2003)
Garcia-Pedrajas, N., Ortiz-Boyer, D.: Boosting k-Nearest Neighbor Classifier by Means of Input Space Projection. Technical Report, Computational Intelligence and Bioinformatics Research Group (2008)
Rambol, R.K., Ahmad, N., Deepak, A.: An Effective Security Management of Database through DNA Fingerprinting Recognition using Geometric Parameters. International Journal of Computer Applications and Information Technology 1(2), 37–38 (2012)
Pelt, J.V., Uylings, H.B., Verwer, R.W., Pentney, R.J., Woldenberg, M.J.: Tree asymmetry – a sensitive and practical measure for binary topological trees. Bulletin of Mathematical Biology 54(5), 759–784 (1992)
Schapire, R.E., Singer, Y.: Improved boosting algorithms using confidence-rated predictions. Machine Learning 37(3), 297–336 (1999)
Friedman, J., Hastie, T., Tibshirani, R.: Additive logistic regression: A statistical view of boosting. The Annals of Statistics 38(2), 337–374 (2000)
Vezhnevets., A., Vezhnevets, V.: Modest AdaBoost – teaching AdaBoost to generalize better. In: Graphicon (2005)
Breiman, L., Friedman, J.H., Olshen, R.A., Stone, C.J.: Classification and Regression Trees. Wadsworth, Belmont (1984)
Ferreira, A.: Survey on Boosting Algorithms for Supervised and Semi-supervised Learning, Instituto de Telecomunicacoes. Technical Report (2007)
Vezhnevets, A.: Moscow State University, MSU Graphics & Media Lab., Computer Vision Group, http://graphics.cs.msu.ru/en/science/research/machinelearning/adaboosttoolbox
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Skoura, A., Nuzhnaya, T., Bakic, P.R., Megalooikonomou, V. (2013). Classifying Ductal Trees Using Geometrical Features and Ensemble Learning Techniques. In: Iliadis, L., Papadopoulos, H., Jayne, C. (eds) Engineering Applications of Neural Networks. EANN 2013. Communications in Computer and Information Science, vol 384. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-41016-1_16
Download citation
DOI: https://doi.org/10.1007/978-3-642-41016-1_16
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-41015-4
Online ISBN: 978-3-642-41016-1
eBook Packages: Computer ScienceComputer Science (R0)