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Protein Structure Prediction Based on Improved Multiple Populations and GA-PSO

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Bio-Inspired Computing - Theories and Applications

Part of the book series: Communications in Computer and Information Science ((CCIS,volume 472))

Abstract

Predicted amino acid sequence of the protein through its spatial structure can be attributed to a multivariable multi extreme global optimization problem. Based on AB off lattice model, a novel hybrid algorithm-MPGPSO which brings together the idea of multiple populations with the improved genetic algorithm and particle swarm optimization algorithm is presented in this paper for searching for the ground state structure of protein. The new algorithm taking advantages of the idea of best of best to enhance the algorithm’s search capability. Experimental results are effective when it is applied to predict the best 3D structure of real protein sequences.

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References

  1. Lee, J.Y., Wu, S., Zhang, Y.: AB Initio Protein Structure Prediction, From Protein Structure to Function with Bioinformatics, pp. 3–25. Springer, Heidelberg (2009)

    Book  Google Scholar 

  2. Zhou, H.B., Lv, Q., We, W.: Stochastic Perturbation PSO Algorithm for Toy Model-based Folding Problem. Computer Engineering and Application 47(18), 234–236 (2011)

    Google Scholar 

  3. Anfinsen, C.B.: Principles That Govern The Folding Of Protein Chains. Science 181, 223 (1973)

    Article  Google Scholar 

  4. Kim, S.Y., Lee, S.B., Lee, J.: Structure Optimization By Conformational Space Annealing In An Off-Lattice Protein Model. Phys. Rev. E 72, 011916 (2005)

    Google Scholar 

  5. Bachmann, M., Arkin, H., Janke, W.: Multicanonical Study Of Coarse-Grained Off-Lattice Models For Folding Heteropolymers. Phys. Rev. E 71, 031906 (2005)

    Google Scholar 

  6. Hsu, H.P., Mehra, V., Grassberger, P.: Structure Optimization in an Off-lattice Protein Model. Phys. Rev. E. 68, 037703 (2003)

    Google Scholar 

  7. Zhou, C.J., Hou, C.X., Zhang, Q., Wei, X.P.: Enhanced Hybrid Search Algorithm for Protein Structure Prediction Using the 3D-HP Lattice Model. Journal of Molecular Modeling 19(9), 3883–3891 (2003)

    Article  Google Scholar 

  8. Sereni, B., Krahenbuhl, L.: Fitness Sharing and Niching Methods Revisited. IEEE Trans. on Evolutionary Computation 2(3), 972–1106 (1998)

    Google Scholar 

  9. Cohoon, J.P., Martin, W.N., Richards, D.S.: A Multi-Population Genetic Algorithm for Solving the K-Partition Problem on Hyper-Cubes. ICGA 91, 244–248 (1991)

    Google Scholar 

  10. Zhou, H.B., Lv, Q.: A Study on Applying Particle Swarm Optimization Algorithm, Soochow University (2009)

    Google Scholar 

  11. Wang, X., Miao, Y., Cheng, M.: Finding Motifs in DNA Sequences Using Low-Dispersion Sequences. Journal of Computational Biology 21(4), 320–329 (2014)

    Article  MathSciNet  Google Scholar 

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Zhou, C., Hu, T., Zhou, S. (2014). Protein Structure Prediction Based on Improved Multiple Populations and GA-PSO. In: Pan, L., Păun, G., Pérez-Jiménez, M.J., Song, T. (eds) Bio-Inspired Computing - Theories and Applications. Communications in Computer and Information Science, vol 472. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45049-9_105

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  • DOI: https://doi.org/10.1007/978-3-662-45049-9_105

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-45048-2

  • Online ISBN: 978-3-662-45049-9

  • eBook Packages: Computer ScienceComputer Science (R0)

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