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Selection of Seeds for Resting-State fMRI-Based Prediction of Individual Brain Maturity

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Bildverarbeitung für die Medizin 2015

Abstract

The analysis of resting-state brain connectivity allows unraveling the fundamentals of functional brain organization. Especially changes of network connectivity related to age or diseases promise to serve as early biomarkers. After control of subject movement, we found that, when reaching a critical number of subjects, age prediction is reproducible for all seed selection strategies tested here (functional, anatomical and random based seeds). On the Enhanced Rockland Community Sample, we use support vector regression (SVR) and intense permutation testing for statistical validation.

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References

  1. Dosenbach NUF, Nardos B, Cohen AL, et al. Prediction of individual brain maturity using fMRI. Science. 2010;329(5997):1358–61.

    Article  Google Scholar 

  2. Power JD, Barnes Ka, Snyder AZ, et al. Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. NeuroImage. 2012;59(3):2142–54.

    Article  Google Scholar 

  3. Tzourio-Mazoyer N, Landeau B, Papathanassiou D, et al. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. NeuroImage. 2002;15(1):273–89.

    Article  Google Scholar 

  4. Shirer WR, Ryali S, Rykhlevskaia E, et al. Decoding subject-driven cognitive states with whole-brain connectivity patterns. Cereb Cortex. 2012;22(1):158–65.

    Article  Google Scholar 

  5. Nooner KB, Colcombe SJ, Tobe RH, et al. The NKI-rockland sample: a model for accelerating the pace of discovery science in psychiatry. Front Neurosci. 2012;6(October): 152.

    Google Scholar 

  6. Chao-Gan Y, Yu-Feng Z. DPARSF: a MATLAB toolbox for ”pipeline” data analysis of resting-state fMRI. Front Syst Neurosci. 2010;4:13.

    Google Scholar 

  7. Chang C, Glover GH. Time-frequency dynamics of resting-state brain connectivity measured with fMRI. NeuroImage. 2010;50(1):81–98.

    Article  Google Scholar 

  8. Mattay VS, Fera F, Tessitore A, et al. Neurophysiological correlates of age-related changes in human motor function. Neurology. 2002;58(4):630–5.

    Article  Google Scholar 

  9. Salat DH, Tuch DS, Greve DN, et al. Age-related alterations in white matter microstructure measured by diffusion tensor imaging. Neurobiol Aging. 2005;26(8):1215–27.

    Article  Google Scholar 

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Correspondence to Norman Scheel .

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Scheel, N., Essenwanger, A., Münte, T., Heldmann, M., Krämer, U., Mamlouk, A. (2015). Selection of Seeds for Resting-State fMRI-Based Prediction of Individual Brain Maturity. In: Handels, H., Deserno, T., Meinzer, HP., Tolxdorff, T. (eds) Bildverarbeitung für die Medizin 2015. Informatik aktuell. Springer Vieweg, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-46224-9_64

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  • DOI: https://doi.org/10.1007/978-3-662-46224-9_64

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  • Publisher Name: Springer Vieweg, Berlin, Heidelberg

  • Print ISBN: 978-3-662-46223-2

  • Online ISBN: 978-3-662-46224-9

  • eBook Packages: Computer Science and Engineering (German Language)

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