Abstract
Micro-robotic cell injection is typically performed manually by a trained bio-operator, and success rates are often low. To enhance bio-operator performance during real-time cell injection, our earlier work introduced a haptically-enabled micro-robotic cell injection system. The system employed haptic virtual fixtures to provide haptic guidance according to particular performance metrics. This paper extends the work by replicating the system within a virtual reality (VR) environment for bio-operator training. Using the virtual environment, the bio-operator is able to control the virtual injection process in the same way they would with the physical haptic micro-robotic cell injection system, while benefiting from the enhanced visualisation capabilities offered by the 3D VR environment. The system is achieved using cost-effective components offering training at much lower cost than using the physical system.
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References
Kuncova, J., Kallio, P.: Challenges in capillary pressure microinjection. In: 26th IEEE Annual International Conference on Engineering in Medicine and Biology Society, pp. 4998–5001 (2004)
Pillarisetti, A., Pekarev, M., Brooks, A.D., Desai, J.P.: Evaluating the role of force feedback for biomanipulation tasks. In: Symposium on Haptic Interfaces for Virtual Environment and Teleoperator Systems, pp. 11–18 (2006)
Yu, S., Nelson, B.J.: Biological cell injection using an autonomous microrobotic system. Int. J. Rob. Res. 21, 861–868 (2002)
Ghanbari, A., Horan, B., Nahavandi, S., Chen, X., Wang, W.: Haptic microrobotic cell injection system. IEEE Syst. J. 8, 1 (2012)
Kimura, Y., Yanagimachi, R.: Intracytoplasmic sperm injection in the mouse. Biol. Reprod. 52, 709–720 (1995)
Ghanbari, A., Abdi, H., Horan, B., Nahavandi, S., Chen, X., Wang, W.: Haptic guidance for microrobotic intracellular injection. In: 3rd IEEE RAS and EMBS International Conference on Biomedical Robotics and Biomechatronics, pp. 162–167 (2010)
Ghanbari, A., Chen, X., Wang, W., Horan, B., Abdi, H., Nahavandi, S.: Haptic microrobotic intracellular injection assistance using virtual fixtures. In: 11th International Conference on Control, Automation, Robotics and Vision, pp. 781–786 (2010)
Wang, W.H., Liu, X.Y., Sun, Y.: High-throughput automated injection of individual biological cells. IEEE Trans. Autom. Sci. Eng. 6(2), 209–219 (2009)
Pillarisetti, A.: Force feedback interface for cell injection. In: Proceedings of 1st Joint Eurohaptics Conference and Symposium on Haptic Interfaces for Virtual Environment and Teleoperator Systems, pp. 391–400 (2005)
Cho, S.Y., Shim, J.H.: A new micro biological cell injection system. In: Proceedings of the IEEE/RSJ IROS International Conference on Intelligent Robots and Systems, pp. 1642–1647 (2004)
Sewell, C., Blevins, N.H., Peddamatham, S., Tan, H.: The effect of virtual haptic training on real surgical drilling proficiency. In: 2nd Joint Eurohaptics Conference and Symposium on Haptic Interfaces for Virtual Environment and Teleoperator Systems, pp. 601–603 (2007)
Basdogan, C., De, S., Kim, J., Muniyandi, M., Kim, H., Srinivasan, M.A.: Haptics in minimally invasive surgical simulation and training. IEEE Comput. Graphics Appl. 24, 56–64 (2004)
Horan, B., Faroque, S., Isaksson, M., Ang, Q.: Reconfigurable multipurpose haptic interface. In: Auvray, M., Duriez, C. (eds.) Haptics: Neuroscience, Devices, Modeling, and Applications, Part II. LNCS, vol. 8619, pp. 432–434. Springer, Heidelberg (2014)
Geomagic, http://geomagic.com/
Kim, J., Janabi-Sharifi, F., Kim, J.: Haptic feedback based on physically based modeling for cellular manipulations systems. In: Ferre, M. (ed.) Haptics: Perception, Devices and Scenarios. LNCS, vol. 5024, pp. 661–667. Springer, Heidelberg (2008)
Horan, B., Lowe, D., Ang, Q-Z., Asgari, M., Ghanbari, A., Nahavandi, S.: Virtual haptic cell model for operator training. In: Proceedings of the 15th International Conference on Mechatronics Technology, pp. 1–5 (2011)
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Faroque, S., Horan, B., Adam, H., Pangestu, M., Thomas, S. (2015). Haptic Virtual Reality Training Environment for Micro-robotic Cell Injection. In: Kajimoto, H., Ando, H., Kyung, KU. (eds) Haptic Interaction. Lecture Notes in Electrical Engineering, vol 277. Springer, Tokyo. https://doi.org/10.1007/978-4-431-55690-9_46
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DOI: https://doi.org/10.1007/978-4-431-55690-9_46
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