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Deadlock Detection in Digital Microfluidics Biochip Droplet Routing

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VLSI Design and Test (VDAT 2018)

Part of the book series: Communications in Computer and Information Science ((CCIS,volume 892))

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Abstract

Digital Microfluidics Biochip (DMFB) is one of the trending research areas. It is used extensively in genetic research and medical diagnostics. Droplet routing is one of the essential tasks in DMFB. The goal is to transport all the droplets to their respective destination cells to perform the desired operation without colliding with each other. To avoid unwanted interference between two droplets, fluidics constraints are defined. Deadlock occurs when two droplets stop advancing to next cell due to the violation of fluidics constraints. This leads to higher routing time. In this paper, we defined the conditions for deadlock and detect the deadlock before its occurrence. The proof is presented also. The simulation result shows improvement in routing time.

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References

  1. Su, F., Hwang, W., Chakrabarty, K.: Droplet routing in the synthesis of digital microfluidic biochips. In: Proceedings of the Conference on Design, Automation and Test in Europe, DATE 2006, Munich, Germany, 6–10 March 2006, pp. 323–328 (2006)

    Google Scholar 

  2. Roy, P., Rahaman, H., Dasgupta, P.: A novel droplet routing algorithm for digital microfluidic biochips. In: Proceedings of the 20th Symposium on Great Lakes Symposium on VLSI, GLSVLSI 2010, Rhode Island, USA, 16–18 May 2010, pp. 441–446 (2010)

    Google Scholar 

  3. Juarez, J., Brizuela, C., Martínez, I., Velázquez, K., Lozano, E.: A genetic algorithm for the routing of droplets in DMFB: preliminary results. In: Proceeding of 2014 IEEE International Conference on Systems, Man and Cybernetics (SMC), San Diego, CA, USA, pp. 3808–3815 (2014)

    Google Scholar 

  4. Bohringer, K.F.: Towards optimal strategies for moving droplets in digital microfluidic systems. In: Proceeding of IEEE International Conference on Robotics and Automation, pp. 1468–1474 (2004)

    Google Scholar 

  5. Griffith, E., Akella, S.: Coordinating multiple droplets in planar array digital microfluidics systems. Int. J. Robot. Res. 24(11), 933–949 (2005)

    Article  Google Scholar 

  6. Akella, S., Griffith, E.J., Goldberg, M.K.: Performance characterization of a reconfigurable planar-array digital microfluidic system. IEEE Trans. Comput. Aided Des. Integr. Circuits Syst. 25, 340–352 (2006)

    Google Scholar 

  7. Yuh, P.H., Yang, C.-L., Chang, Y.-W.: BioRoute: a network-flow based routing algorithm for digital microfluidic biochips. In: Proceeding of IEEE/ACM Computer-Aided Design, ICCAD 2007, San Jose, CA, USA, 4–8 November 2007

    Google Scholar 

  8. Xu, T., Chakrabarty, K.: A cross-referencing-based droplet manipulation method for high-throughput and pin-constrained digital microfluidic arrays. In: Proceedings of Design Automation and Test in Europe, April 2007, pp. 552–557 (2007)

    Google Scholar 

  9. Yuh, P.-H., Sapatnekar, S., Yang, C.-L., Chang, Y.-W.: A progressive-ILP based routing algorithm for Cross referencing biochips. In: Proceedings of Design Automation Conference, June 2008, pp. 284–289 (2008)

    Google Scholar 

  10. Cho, M., Pan, D.Z.: A high-performance droplet routing algorithm for digital microfluidic biochips. IEEE Trans. Comput. Aided Des. Integr. Circuits Syst. 27(10), 406–419 (2008)

    Google Scholar 

  11. Huang, T., Ho, T.: A fast routability - and performance-driven droplet routing algorithm for digital microfluidic biochips. In: Proceedings of IEEE ICCD, Lake Tahoe, CA, pp. 445–450 (2009)

    Google Scholar 

  12. Zhao, Y., Chakrabarty, K.: Cross-contamination avoidance for droplet routing in digital microfluidic biochips. In: Proceeding of Conference on Design, Automation and Test in Europe, DATE 2009, Nice, France, 20–24 April 2009, pp. 1290–1295 (2009)

    Google Scholar 

  13. Roy, P., Bhattacharya, R., Rahaman, H., Dasgupta, P.: A best path selection based parallel router for DMFBs. In: IEEE International Symposium on Electronic Design, ISED 2011, Kochi, India, pp. 176–181 (2011)

    Google Scholar 

  14. Roy, P., Rahaman, H., Dasgupta, P.: Two-level clustering-based techniques for intelligent droplet routing in digital microfluidic biochips. Integr. 45(3), 316–330 (2012)

    Article  Google Scholar 

  15. Pan, I., Dasgupta, P., Rahaman, H., Samanta, T.: Ant colony optimization based droplet routing technique in digital microfluidic biochip. In: International Symposium on Electronic System Design, pp. 223–229 (2011)

    Google Scholar 

  16. Roy, P., Howladar, P., Bhattacharjee, R., Rahaman, H., Dasgupta, P.: A new cross contamination aware routing method with intelligent path exploration in digital microfluidic biochips. In: Proceedings of 8th International Conference on Design & Technology of Integrated Systems in Nanoscale Era, (DTIS), Abu Dhabi, United Arab Emirates, 26–28 March 2013

    Google Scholar 

  17. Pan, I., Samanta, T.: Weighted optimization of various parameters for droplet routing in digital microfluidic biochips. In: Thampi, S., Abraham, A., Pal, S., Rodriguez, J. (eds.) Recent Advances in Intelligent Informatics. AISC, vol. 235, pp. 131–139. Springer, Cham (2004). https://doi.org/10.1007/978-3-319-01778-5_14

    Chapter  Google Scholar 

  18. Wang, Q., Shen, Y., Yao, H., Ho, T.-Y., Cai, Y.: Contamination-aware routing flow for both functional and washing droplets in digital microfluidic biochips. In: Proceeding of 19th Workshop on Synthesis And System Integration of Mixed Information technologies, (SASIMI 2015), Yilan, Taiwan (2015)

    Google Scholar 

  19. Bhattacharya, R., Rahaman, H., Roy, P.: A new heterogeneous droplet routing technique and its simulator to improve route performance in digital microfluidic biochips. In: Proceedings of 2016 International Conference on Microelectronics, Computing and Communications, MicroCom, Durgapur, India, 23–25 January 2016

    Google Scholar 

  20. Maftei, E., Pop, P., Madsen, J.: Routing-based synthesis of digital microfluidic biochips. In: Proceedings of International Conference on Compilers, Architectures and Synthesis for Embedded Systems (CASES 2010), Scottsdale, Arizona, USA, 24–29 October 2010, pp. 41–50 (2010)

    Google Scholar 

  21. Grissom, D., Brisk, P.: A high-performance online assay interpreter for digital microfluidic biochips. In: Proceedings of the 22nd Great Lake Symposium on VLSI, (GLS-VLSI), Salt Lake City, UT, USA, 3–4 May 2012, pp. 103–106 (2012)

    Google Scholar 

  22. Grissom, D., Brisk, P.: Fast online synthesis of digital microfluidic biochips. IEEE Trans. Comput. Aided Des. Integr. Circuits Syst. (TCAD) 33(3), 356–369 (2014)

    Article  Google Scholar 

  23. Grissom, D., Brisk, P.: Path scheduling on digital microfluidic biochips. In: Proceedings of 49th Design Automation Conference, (DAC), San Francisco, CA, USA, 3–7 June 2012, pp. 26–35 (2012)

    Google Scholar 

  24. Bhattacharya, R., Roy, P., Rahaman, H.: Homogeneous droplet routing in DMFB: an enhanced technique for high performance bioassay implementation. Integr. VLSI J. 60, 74–91 (2018)

    Article  Google Scholar 

  25. Sait, S., Youssef, H.: VLSI Physical Design Automation: Theory and Practice. IEEE Press, New York (1995)

    Google Scholar 

  26. Singha, K., Samanta, T., Rahaman, H., Dasguptay, P.: Method of droplet routing in digital microfluidic biochip. In: Proceeedings of the 2010 IEEE/ASME International Conference on Mechatronics and Embedded Systems and Applications (MESA), QingDao, China, 15–17 July 2010

    Google Scholar 

  27. Bazargan, K., Kastner, R., Sarrafzadeh, M.: Fast template placement for reconfigurable computing systems. IEEE Des. Test Comput. 17(1), 68–83 (2000)

    Article  Google Scholar 

  28. Grissom, D., et al.: An open-source compiler and PCB synthesis tool for digital microfluidic biochips. Integr. VLSI J. 51, 169–193 (2015)

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Computer Science and Engineering, National Institute of Technology, Rourkela, 769008, Odisha, India

    Jyotiranjan Swain & Sumanta Pyne

Authors
  1. Jyotiranjan Swain
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  2. Sumanta Pyne
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Correspondence to Jyotiranjan Swain .

Editor information

Editors and Affiliations

  1. Thiagarajar College of Engineering, Madurai, India

    S. Rajaram

  2. Thiagarajar College of Engineering, Madurai, India

    N.B. Balamurugan

  3. Thiagarajar College of Engineering, Madurai, India

    D. Gracia Nirmala Rani

  4. Indian Institute of Technology Bombay, Mumbai, India

    Virendra Singh

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Swain, J., Pyne, S. (2019). Deadlock Detection in Digital Microfluidics Biochip Droplet Routing. In: Rajaram, S., Balamurugan, N., Gracia Nirmala Rani, D., Singh, V. (eds) VLSI Design and Test. VDAT 2018. Communications in Computer and Information Science, vol 892. Springer, Singapore. https://doi.org/10.1007/978-981-13-5950-7_21

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  • DOI: https://doi.org/10.1007/978-981-13-5950-7_21

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-13-5949-1

  • Online ISBN: 978-981-13-5950-7

  • eBook Packages: Computer ScienceComputer Science (R0)

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