Abstract
In this work, we propose an automated system for the personalization of retina laser treatment in diabetic retinopathy. The system comprises fundus images processing methods, algorithms for photocoagulation pattern mapping, and intelligent analysis methods of OCT data and fundus images. The feasibility of introducing corrections at any interim stage of data processing makes for a safe treatment. A key module of the proposed software architecture is the system for the intelligent analysis of the photocoagulation pattern, allowing the proposed plan to be analyzed and the treatment outcome to be prognosticated. Working with the proposed system, the surgeon is able to map an effective photocoagulation pattern, which is aimed at providing a higher-quality diabetic retinopathy laser treatment when compared with the current approaches. The software developed is intended for the use of high-performance algorithms that can be parallelized using either a processor or a graphics processing unit. This allows achieving high data processing speed, which is so important for medical systems.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Rottier, J.B.: Artificial intelligence: reinforcing the place of humans in our healthcare system. Rev. Prat. 68(10), 1150–1151 (2018)
Fourcade, A., Khonsari, R.H.: Deep learning in medical image analysis: A third eye for doctors. J. Stomatol. Oral Maxillofacial Surg. 120(4), 279–288 (2019)
Gao, A., et al.: Progress in robotics for combating infectious diseases. Sci. Robot. 6(52), 1–17 (2021)
Trinh, M., Ghassibi, M., Lieberman, R.: Artificial Intelligence in retina. Adv. Ophthalmol. Optometry 6, 175–185 (2021)
Vorobieva, I.V., Merkushenkova, D.A.: Diabetic retinopathy in patients with type 2 Diabetes Mellitus. Epidemiology, a modern view of pathogenesis. Ophthalmology 9(4), 18–21 (2012)
Dedov, I.I., Shestakova, M.V., Galstyan, G.R.: Prevalence of type 2 Diabetes Mellitus in the adult population of Russia (NATION study). Diabetes mellitus 19(2), 104–112 (2016)
Tan, G.S., Cheung, N., Simo, R.: Diabetic macular edema. Lancet Diab. Endoc 5, 143–155 (2017)
Amirov, A.N., Abdulaeva, E.A., Minkhuzina, E.L.: Diabetic macular edema: Epidemiology, pathogenesis, diagnosis, clinical presentation, and treatment. Kazan Med. J. 96(1), 70–74 (2015)
Doga, A.V., Kachalina, G.F., Pedanova, E.K., Buryakov, D.A.: Modern diagnostic and treatment aspects of diabetic macular edema. Ophthalmol. Diabetes 4, 51–59 (2014)
Bratko, G.V., Chernykh, V.V., Sazonova, O.V.: On early diagnostics and the occurence rate of diabetic macular edema and identification of diabetes risk groups. Siberian Sci. Med. J. 35(1), 33–36 (2015)
Wong, T.Y., Liew, G., Tapp, R.J.: Relation between fasting glucose and retinopathy for diagnosis of diabetes: three population-based cross-sectional studies. Lancet 371(9614), 736–743 (2008)
Acharya, U.R., Ng, E.Y., Tan, J.H., Sree, S.V., Ng, K.H.: An integrated index for the identification of diabetic retinopathy stages using texture parameters. J. Med. Syst. 36(3), 2011–2020 (2012)
Astakhov, Yu.S., Shadrichev, F.E., Krasavina, M.I., Grigorieva, N.N.: Modern approaches to the treatment of diabetic macular edema. Ophthalmol. Statements 4, 59–69 (2009)
Zamytsky, E.A., Zolotarev, A.V., Karlova, E.V., Zamytsky, P.A.: Analysis of the coagulates intensity in laser treatment of diabetic macular edema in a Navilas robotic laser system. Saratov J. Med. Sci. Res. 13(2), 375–378 (2017)
Zamytskiy, E.A., Zolotarev, A.V., Karlova, E.V., et al.: Comparative quantitative assessment of the placement and intensity of laser spots for treating diabetic macular edema. Russ. J. Clin. Ophthalmol. 21(2), 58–62 (2021)
Kotsur, T.V., Izmailov, A.S.: The effectiveness of laser coagulation in the macula and high-density microphotocoagulation in the treatment of diabetic maculopathy. Ophthalmol. Statements 9(4), 43–45 (2016)
Kozak, I., Luttrull, J.: Modern retinal laser therapy. Saudi J. Ophthalmol. 29(2), 137–146 (2014)
Kernt, M., Cheuteu, R., Liegl, R.: Navigated focal retinal laser therapy using the NAVILAS® sys-tem for diabetic macula edema. Ophthalmologe 109, 692–700 (2012)
Ober, M.D.: Time required for navigated macular laser photo coagulation treatment with the Navilas®. Graefes Arch. Clin. Exp. Ophthalmol 251(4), 1049–1053 (2013)
Syeda, A.M., Hassanb, T., Akramc, M.U., Nazc, S., Khalid, S.: Automated diagnosis of macular edema and central serous retinopathy through robust reconstruction of 3D retinal surfaces. Comput. Methods Programs Biomed. 137, 1–10 (2016)
Chhablani, J., Kozak, I., Barteselli, G., Oman, S. El-E.: A novel navigated laser system brings new efficacy to the treatment of retinovascular disorders. J. Ophthalmol. 6(1), 18–22 (2013)
Septiarini, A., Harjoko, A., Pulungan, R., Ekantini, R.: Automatic detection of peripapillary atrophy in retinal fundus images using statistical features. Biomed. Signal Process. Control 45, 151–159 (2018)
Hei Shun, Yu., Tischler, B., Qureshi, M.M., Soto, J.A., Anderson, S., Daginawala, N., Li, B., Buch, K.: Using texture analyses of contrast enhanced CT to assess hepatic fibrosis. Eur. J. Radiol. 85(3), 511-517 (2016)
Ilyasova, N., Paringer, R., Kupriyanov, A.: Intelligent feature selection technique for segmentation of fundus images. In: 7th International Conference on Innovative Computing Technology, pp. 138–143. Luton, UK (2017)
Anan’in, M.A., Ilyasova, N.Yu., Kupriyanov, A.V.: Estimating directions of optic disk blood vessels in retinal images. Pattern Recogn. Image Anal. Adv. Math. Theory Appl. 17(4), 523–526 (2007)
Mukhin, A., Kilbas, I., Paringer, R., Ilyasova, N.: Application of the gradient descent for data balancing in diagnostic image analysis problems. In: 2020 International Conference on Information Technology and Nanotechnology, pp. 1–4. IEEE Xplore, Russia (2020)
Ilyasova, N.Yu., Shirokanev, A.S., Kupriynov, A.V., Paringer, R.A.: Technology of intellectual feature selection for a system of automatic formation of a coagulate plan on retina. Computer Opt. 43(2), 304–315 (2019)
Shirokanev, A.S., Kirsh, D.V., Ilyasova, N.Yu., Kupriynov, A.V.: Investigation of algorithms for coagulate arrangement in fundus images. Computer Opt. 42(4), 712–721 (2018)
Kazakov, A.L., Lebedev, P.D.: Algorithms of optimal packing construction for planar compact sets. Comput. Methods Program. 16, 307–317 (2015)
Tamborski, S., Wróbel, K., Bartuzel, M., Szkulmowski, M.: Spectral and time domain optical coherence spectroscopy. Opt. Lasers Eng. 133, 106120 (2020)
Shirokanev, A., Ilyasova, N., Andriyanov, N., Zamytskiy, E., Zolotarev, A., Kirsh, D.: Modeling of fundus laser exposure for estimating safe laser coagulation parameters in the treatment of diabetic retinopathy. Mathematics 9, 967 (2021)
Shirokanev, A.S., Andriyanov, N.A., Ilyasova, N.Y.: Development of vector algorithm using CUDA technology for three-dimensional retinal laser coagulation process modeling. Comput. Opt. 45(3), 427–437 (2021)
Fukunaga, K.: Introduction to Statistical Pattern Recognition. Academic, New York (1979)
Acknowledgements
This work was funded by the Russian Foundation for Basic Research under RFBR grants ## 19-29-01135 and the Ministry of Science and Higher Education of the Russian Federation within a government project of FSRC “Crystallography and Photonics” RAS.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2022 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
About this paper
Cite this paper
Ilyasova, N., Demin, N., Shirokanev, A., Andriyanov, N. (2022). Automated System for the Personalization of Retinal Laser Treatment in Diabetic Retinopathy Based on the Intelligent Analysis of OCT Data and Fundus Images. In: Czarnowski, I., Howlett, R.J., Jain, L.C. (eds) Intelligent Decision Technologies. Smart Innovation, Systems and Technologies, vol 309. Springer, Singapore. https://doi.org/10.1007/978-981-19-3444-5_15
Download citation
DOI: https://doi.org/10.1007/978-981-19-3444-5_15
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-19-3443-8
Online ISBN: 978-981-19-3444-5
eBook Packages: Intelligent Technologies and RoboticsIntelligent Technologies and Robotics (R0)