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TCSA: A Text-Guided Cross-View Medical Semantic Alignment Framework forĀ Adaptive Multi-view Visual Representation Learning

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Bioinformatics Research and Applications (ISBRA 2023)

Part of the book series: Lecture Notes in Computer Science ((LNBI,volume 14248))

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Abstract

Recently, in the medical domain, visual-language (VL) representation learning has demonstrated potential effectiveness in diverse medical downstream tasks. However, existing works typically pre-trained on the one-to-one corresponding medical image-text pairs, disregarding fluctuation in the quantity of views corresponding to reports (e.g., chest X-rays typically involve 1 to 3 projection views). This limitation results in sub-optimal performance in scenarios with varying quantities of views (e.g., arbitrary multi-view classification). To address this issue, we propose a novel Text-guided Cross-view Semantic Alignment (TCSA) framework for adaptive multi-view visual representation learning. For arbitrary number of multiple views, TCSA learns view-specific private latent sub-spaces and then maps them to a scale-invariant common latent sub-space, enabling individual treatment of arbitrary view type and normalization of arbitrary quantity of views to a consistent scale in the common sub-space. In the private sub-spaces, TCSA leverages word context as guidance to match semantic corresponding sub-regions across multiple views via cross-modal attention, facilitating alignment of different types of views in the private sub-space. This promotes the combination of information from arbitrary multiple views in the common sub-space. To the best of our knowledge, TCSA is the first VL framework for arbitrary multi-view visual representation learning. We report the results of TCSA on multiple external datasets and tasks. Compared with the state of the art frameworks, TCSA achieves competitive results and generalize well to unseen data.

This work was supported by the National Key Research and Development Program (2021YFF0703704); Guangdong Basic and Applied Basic Research Foundation (2022A1515011217 and 2022A1515011557)); National Natural Science Foundation of China (U1913210 and 62206269); Shenzhen Science and Technology Program (JSGG20211029095546003 and JCYJ20190807161805817).

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Notes

  1. 1.

    https://github.com/marshuang80/gloria.

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Correspondence to Dan Wu .

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Lei, H. et al. (2023). TCSA: A Text-Guided Cross-View Medical Semantic Alignment Framework forĀ Adaptive Multi-view Visual Representation Learning. In: Guo, X., Mangul, S., Patterson, M., Zelikovsky, A. (eds) Bioinformatics Research and Applications. ISBRA 2023. Lecture Notes in Computer Science(), vol 14248. Springer, Singapore. https://doi.org/10.1007/978-981-99-7074-2_11

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  • DOI: https://doi.org/10.1007/978-981-99-7074-2_11

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