Skip to main content

Enhancing Clustering Performance in Sepsis Time Series Data Using Gravity Field

  • Conference paper
  • First Online:
Health Information Science (HIS 2023)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 14305))

Included in the following conference series:

Abstract

Sepsis, a severe systemic response to infection, represents a pressing global public health challenge. Time series research, including the analysis of medical data, encounters significant obstacles due to the high dimensionality, complexity, and heterogeneity inherent in the data associated with sepsis. To address these obstacles, this paper proposes a novel approach for enhancing time series datasets. The primary objective of this approach is to enhance clustering performance and robustness without requiring modifications to existing clustering techniques. Specifically, this approach can improve the clustering performance in sepsis patients. The effectiveness of the proposed approach is validated through comprehensive experiments conducted on both non-medical and medical sepsis datasets, showcasing its potential to advance time series analysis and significantly contribute to the effective management of sepsis medical conditions. In addition, we use this approach to establish three subtypes in the clustering of sepsis patients, which provide meaningful interpretations in terms of medical significance and we further explore the therapeutic heterogeneity among the three subtypes.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 74.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Blekas, K., Lagaris, I.: Newtonian clustering: an approach based on molecular dynamics and global optimization. Pattern Recognit. 40(6), 1734–1744 (2007). https://doi.org/10.1016/j.patcog.2006.07.012, https://www.sciencedirect.com/science/article/pii/S0031320306003463

  2. Fleischmann, C., et al.: Assessment of global incidence and mortality of hospital-treated sepsis. Current estimates and limitations. Am. J. Respir. Crit. Care Med. 193(3), 259–272 (2016). https://doi.org/10.1164/rccm.201504-0781OC

    Article  Google Scholar 

  3. Li, Q., Wang, S., Zhao, C., Zhao, B., Yue, X., Geng, J.: HIBOG: improving the clustering accuracy by ameliorating dataset with gravitation. Inf. Sci. 550, 41–56 (2021). https://doi.org/10.1016/j.ins.2020.10.046, https://www.sciencedirect.com/science/article/pii/S0020025520310392

  4. Mudelsee, M.: Trend analysis of climate time series: a review of methods. Earth-Sci. Rev. 190, 310–322 (2019)

    Article  Google Scholar 

  5. Rakthanmanon, T., et al.: Searching and mining trillions of time series subsequences under dynamic time warping. In: Proceedings of the ACM SIGKDD International Conference on Knowledge Discovery and Data Mining (KDD), pp. 262–270 (2012). https://doi.org/10.1145/2339530.2339576

  6. Rehman, O., Al-Busaidi, A.M., Ahmed, S., Ahsan, K.: Ubiquitous healthcare system: architecture, prototype design and experimental evaluations. EAI Endors. Trans. Scalable Inf. Syst. 9(4) (2022). https://doi.org/10.4108/eai.5-1-2022.172779

  7. Rhee, C., et al.: Incidence and trends of sepsis in us hospitals using clinical vs claims data, 2009–2014. JAMA 318(13), 1241–1249 (2017). https://doi.org/10.1001/jama.2017.13836

    Article  Google Scholar 

  8. Rudd, K.E., et al.: Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the global burden of disease study. Lancet 395(10219), 200–211 (2020). https://doi.org/10.1016/S0140-6736(19)32989-7

    Article  Google Scholar 

  9. Sarki, R., Ahmed, K., Wang, H., Zhang, Y., Wang, K.: Convolutional neural network for multi-class classification of diabetic eye disease. EAI Endors. Trans. Scalable Inf. Syst. 9(4) (2021). https://doi.org/10.4108/eai.16-12-2021.172436

  10. Seymour, C.W., et al.: Precision medicine for all? Challenges and opportunities for a precision medicine approach to critical illness. Crit. Care 21(1), 257 (2017). https://doi.org/10.1186/s13054-017-1836-5

    Article  Google Scholar 

  11. Shi, Y., Song, Y., Zhang, A.: A shrinking-based clustering approach for multidimensional data. IEEE Trans. Knowl. and Data Eng. 17(10), 1389–1403 (2005). https://doi.org/10.1109/TKDE.2005.157

    Article  Google Scholar 

  12. Siddiqui, S.A., Fatima, N., Ahmad, A.: Chest X-ray and CT scan classification using ensemble learning through transfer learning. EAI Endors. Trans. Scalable Inf. Syst. 9(6) (2022). https://doi.org/10.4108/eetsis.vi.382

  13. Stoffer, D., Ombao, H.: Editorial: special issue on time series analysis in the biological sciences. J. Time Ser. Anal. 33(5), 701–703 (2012). https://doi.org/10.1111/j.1467-9892.2012.00805.x

    Article  MathSciNet  MATH  Google Scholar 

  14. Schmierer, T., Li, T., Li, Y.: A novel empirical wavelet SODP and spectral entropy based index for assessing the depth of anaesthesia. Health Inf. Sci. Syst. 10(1), 10 (2022). https://doi.org/10.1007/s13755-022-00178-8

    Article  Google Scholar 

  15. Vincent, J.L.: The coming era of precision medicine for intensive care. Crit. Care 21(Suppl 3), 314 (2017). https://doi.org/10.1186/s13054-017-1910-z

    Article  Google Scholar 

  16. Wong, H.R., et al.: Identification of pediatric septic shock subclasses based on genome-wide expression profiling. BMC Med. 7, 34 (2009). https://doi.org/10.1186/1741-7015-7-34

    Article  Google Scholar 

  17. Wong, H.R., et al.: Validation of a gene expression-based subclassification strategy for pediatric septic shock. Crit. Care Med. 39(11), 2511–2517 (2011). https://doi.org/10.1097/CCM.0b013e3182257675

    Article  Google Scholar 

  18. Wong, K.C., Peng, C., Li, Y., Chan, T.M.: Herd clustering: a synergistic data clustering approach using collective intelligence. Appl. Soft Comput. 23, 61–75 (2014). https://doi.org/10.1016/j.asoc.2014.05.034, https://www.sciencedirect.com/science/article/pii/S1568494614002610

  19. Pang, X., Ge, Y.F., Wang, K., Traina, A.J., Wang, H.: Patient assignment optimization in cloud healthcare systems: a distributed genetic algorithm. Health Inf. Sci. Syst. 11(1), 30 (2023). https://doi.org/10.1007/s13755-023-00230-1

    Article  Google Scholar 

  20. Xie, J., et al.: The epidemiology of sepsis in Chinese ICUs: a national cross-sectional survey. Crit. Care Med. 48(3), e209–e218 (2020). https://doi.org/10.1097/CCM.0000000000004155

    Article  Google Scholar 

  21. Zhang, Y., et al.: A heterogeneous multi-modal medical data fusion framework supporting hybrid data exploration. Health Inf. Sci. Syst. 10(1), 22 (2022). https://doi.org/10.1007/s13755-022-00183-x

    Article  MathSciNet  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Rui Hao .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Hao, R. et al. (2023). Enhancing Clustering Performance in Sepsis Time Series Data Using Gravity Field. In: Li, Y., Huang, Z., Sharma, M., Chen, L., Zhou, R. (eds) Health Information Science. HIS 2023. Lecture Notes in Computer Science, vol 14305. Springer, Singapore. https://doi.org/10.1007/978-981-99-7108-4_17

Download citation

  • DOI: https://doi.org/10.1007/978-981-99-7108-4_17

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-99-7107-7

  • Online ISBN: 978-981-99-7108-4

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics