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A neural network trained to identify the presence of myocardial infarction bases diagnostic decision on nonlinear relationships between input variables

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Abstract

To determine whether an artificial neural network trained to recognize the presence of acute myocardial infarction makes clinical decisions based on nonlinear relationships it establishes between inputted information, a linear and nonlinear network with identical number of input nodes were trained and then tested on identical pattern sets. The ratio of residual variances between the two networks was 0.726. The linear and nonlinear networks made 21 and 9 errors, respectively, on 350 test patterns. The use of nonlinear relationships was further studied by trending the quantitative effect on network output resulting from the modification of single clinical input variables in 706 specific patterns derived from patients presenting with anterior chest pain. This revealed that the distribution of the effect on network output was bimodally distributed in 8 of the 20 clinical input variables utilized by the network. The basis for this distribution was due to the network placing markedly different diagnostic importance on the same variable in different patterns. This appears to be the first instance in which nonlinear logic has been shown to improve upon clinical decision-making.

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Baxt, W.G. A neural network trained to identify the presence of myocardial infarction bases diagnostic decision on nonlinear relationships between input variables. Neural Comput & Applic 1, 176–182 (1993). https://doi.org/10.1007/BF01414944

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  • DOI: https://doi.org/10.1007/BF01414944

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