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Biological structure determination by EM is well suited to grid computing

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Conclusion

This short note describes a potential application of grid computing in life sciences: high resolution structure determination of biological specimens by electron microscope tomography. It is shown there are excellent opportunities to benefit from grids: potential intensive applications to exploit the “high-throughput” and the “distributed supercomputing” capabilities of grids. Furthermore, grids may turn into reality solving problems not dared so far, such as structure determination of large viruses at near-atomic resolution or reconstruction of whole cells at molecular resolution. Grid computing will make it possible to afford those “grand challenge” applications currently unapproachable.

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Authors and Affiliations

  1. Department of Computer Architecture, Universidad Almeria, Almeria, Spain

    Jose-Jesus Fernandez & Inmaculada Garcia

  2. Centro Nacional Biotecnologia, Universidad Autonoma, Madrid, Spain

    Jose-Roman Bilbao-Castro & Jose-Maria Carazo

  3. Department of Computer Science, Universidad Autonoma, Madrid, Spain

    Roberto Marabini

Authors
  1. Jose-Jesus Fernandez
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  2. Jose-Roman Bilbao-Castro
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  3. Roberto Marabini
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  4. Jose-Maria Carazo
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  5. Inmaculada Garcia
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Fernandez, JJ., Bilbao-Castro, JR., Marabini, R. et al. Biological structure determination by EM is well suited to grid computing. New Gener Comput 22, 187–188 (2004). https://doi.org/10.1007/BF03040957

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  • DOI: https://doi.org/10.1007/BF03040957

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