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Visualising cerebral asymmetry

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Visualization in Biomedical Computing (VBC 1996)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 1131))

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Abstract

We describe techniques for visualising and measuring the asymmetry of the cerebral hemispheres based on MRI scans. These techniques improve on previous approaches in two ways: firstly, measurements are not limited to voxel discretisation scales; secondly, symmetry measurements are inherently 3D. This avoids the errors in slice-based measurements arising from shape distortions introduced by misalignment between the head and MRI machine.

We focus on ‘sparse’ MRI data sets in which the slices are non-contiguous, since these constitute an important source of data in longitudinal neurological studies. Two visualisations of asymmetry are presented. The first is 3D and enables an immediate qualitative appreciation of the disposition of the asymmetry. The second is a 2D rendering of the symmetry map, a quantitative measure of asymmetry across the brain.

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References

  1. R. M. Bilder. Absence of regional hemispheric volume asymmetries in first-episode schizophrenia. American Journal of Psychiatry, 151(10):1437–1447, Oct 1994.

    Google Scholar 

  2. A. Blake, R. Curwen, and A. Zisserman. A framework for spatiotemporal control in the tracking of visual contours. Intl. Journal of Comp. Vis., 11(2):127–145, 1993.

    Google Scholar 

  3. T. J. Crow. Temporal lobe asymmetry as the key to the aetiology of schizophrenia. Schizophrenia Bulletin, 16:433–443, 1990.

    Google Scholar 

  4. L. DeLisi. Loss of normal cerebral asymmetries in first-episode schizophrenia. To appear: Archives General Psychiatry, December 1994.

    Google Scholar 

  5. J. Feldmar. Rigid, non-rigid and protective registration of medical images. PhD thesis, Ecole Polytechnique, 1995.

    Google Scholar 

  6. M. Kass, A. Witkin, and Terzopoulus. Snakes: Active contour models. Proc. First Intl. Conf. on Comput. Vis., pages 259–268, 1987.

    Google Scholar 

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Karl Heinz Höhne Ron Kikinis

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© 1996 Springer-Verlag Berlin Heidelberg

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Marais, P., Guillemaud, R., Sakuma, M., Zisserman, A., Brady, M. (1996). Visualising cerebral asymmetry. In: Höhne, K.H., Kikinis, R. (eds) Visualization in Biomedical Computing. VBC 1996. Lecture Notes in Computer Science, vol 1131. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0046981

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  • DOI: https://doi.org/10.1007/BFb0046981

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-61649-8

  • Online ISBN: 978-3-540-70739-4

  • eBook Packages: Springer Book Archive

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