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Using Web technologies and meta-computing to visualise a simplified simulation model of tumor growth in vitro

  • Workshop: IEEE EMBS ITIS-ITAB'99
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High-Performance Computing and Networking (HPCN-Europe 1999)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 1593))

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Abstract

The aim of this paper is to demonstrate the impact that Web technologies and meta computing can have on the simulation of biological processes such as tumor growth. A client-server architecture allowing real time surface and volume rendering using a standard Web browser is proposed. A simplified three-dimensional cytokinetic simulation model of tumor growth in vitro is developed and results are obtained concerning the development of a small cell lung cancer (SCLC) tumor spheroid in cell culture. A Gaussian distribution of the cell cycle phase durations is considered. The behavior of the model is compared with both published data and laboratory experience. The application of Web technologies and meta computing leads to a spectacular three-dimensional visualisation of both the external and the internal structure of a growing tumor spheroid.

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Authors and Affiliations

  1. Department of Electrical and Computer Engineering, Division of Electroscience, National Technical University of Athens, 157 80 Zografou, Athens, Greece

    Georgios S. Stamatakos, Evangelia I. Zacharaki, Nikolaos A. Mouravliansky, Konstantinos K. Delibasis, Konstantina S. Nikita, Nikolaos K. Uzunoglu & Andy Marsh

Authors
  1. Georgios S. Stamatakos
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  2. Evangelia I. Zacharaki
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  3. Nikolaos A. Mouravliansky
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  4. Konstantinos K. Delibasis
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  5. Konstantina S. Nikita
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  6. Nikolaos K. Uzunoglu
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  7. Andy Marsh
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Peter Sloot Marian Bubak Alfons Hoekstra Bob Hertzberger

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© 1999 Springer-Verlag

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Stamatakos, G.S. et al. (1999). Using Web technologies and meta-computing to visualise a simplified simulation model of tumor growth in vitro. In: Sloot, P., Bubak, M., Hoekstra, A., Hertzberger, B. (eds) High-Performance Computing and Networking. HPCN-Europe 1999. Lecture Notes in Computer Science, vol 1593. Springer, Berlin, Heidelberg . https://doi.org/10.1007/BFb0100658

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  • DOI: https://doi.org/10.1007/BFb0100658

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-65821-4

  • Online ISBN: 978-3-540-48933-7

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