Abstract
Speckle noise is a granular artifact in medical ultrasound images. It causes serious problems and hinders the development of automatic diagnosis technology. In this paper, a novel and integrated approach is proposed to address the de-noising problem by using wavelet transformation and trilateral filter. Firstly, a dynamic additive model is developed to account for the medical ultrasound signal with speckle noise. Secondly, in accordance with the statistical property of the additive model, an adaptive wavelet shrinkage algorithm is applied to the noisy medical signal. Particularly, the algorithm is significant to the high-frequency component of the speckle noise in the wavelet domain. Thirdly, but most importantly, the low-frequency component of the speckle noise is suppressed by a trilateral filter. It simultaneously reduces the speckle and impulse noise in real set data. Finally, a lot of experiments are conducted on both synthetic images and real clinical ultrasound images for authenticity. Compared with other existing methods, experimental results show that the proposed algorithm demonstrates an excellent de-noising performance, offers great flexibility and substantially sharpens the desirable edge.






Similar content being viewed by others
References
K.Z. Abd-Elmoniem, A.B. Youssef, Y.M. Kadah, Real-time speckle reduction and coherence enhancement in ultrasound imaging via nonlinear anisotropic diffusion. IEEE Trans. Biomed. Eng. 49, 997–1014 (2002)
G. Andria, F. Attivissimo, G. Cavone, Linear filtering of 2-D wavelet coefficients for denoising ultrasound medical images. Measurement. 45, 1792–1800 (2012)
S. Balocco, C. Gatta, O. Pujol, SRBF: speckle reducing bilateral filtering. Ultrasound Med. Biol. 36, 1353–1363 (2010)
R.H.T. Bates, B.S. Robinson, Ultrasonic transmission speckle imaging. Ultrason. Imaging. 3, 378–394 (1981)
C.B. Burckhardt, Speckle in ultrasound B-mode scans. IEEE Trans. Sonics Ultrason. 25, 1–6 (1978)
D.L.D. Charles-Alban, T. Florence, Iterative weighted maximum likelihood denoising with probabilistic patch-based weights. IEEE Trans. Image Process. 18, 2661–2672 (2009)
D.L. Donoho, I.M. Johnstone, Ideal spatial adaptation via wavelet shrinkage. Biometrika. 81, 425–455 (1994)
V. Dutt, Statistical analysis of ultrasound echo envelope. PhD Dissertation, Mayo Graduate School (1995)
V.S. Frost, J.A. Stiles, K.S. Shanmugan, A model for radar images and its application to adaptive digital filtering of multiplicative noise. IEEE Trans. Pattern Anal. Mach. Intell. 2, 157–166 (1982)
W. Gao, L. Yang, X. Zhang, Based on soft-threshold wavelet de-noising combining with Prewitt operator edge detection algorithm. IEEE Int. Conf. Educ. Technol. Comput. 10, 155–162 (2010)
R. Garnett, T. Huegerich, C. Chui, A universal noise removal algorithm with an impulse detector. IEEE Trans. Image Process. 14, 1747–1754 (2005)
J.W. Goodman, Some fundamental properties of speckle. J. Opt. Soc. Am. 66, 1145–1150 (1976)
K. Karl, W. Carl-Fredrik, K. Ron, Oriented speckle reducing anisotropic diffusion. IEEE Trans. Image Process. 16, 1412–1424 (2007)
J.S. Lee, Digital image enhancement and noise filtering by use of local statistics. IEEE Trans. Pattern Anal. Mach. Intell. 2, 165–168 (1980)
Y. Lin, B. Fang, Y. Tang, Image restoration using fuzzy impulse noise detection and adaptive median filter, in Pattern Recognition (CCPR), 2010 Chinese Conference on (IEEE, 2010), pp. 1–4
MathWorks. Wavelet Toolbox (2013)
G. Nikhil, M.N.S. Swamy, P. Eugene, Despeckling of medical ultrasound images using data and rate adaptive lossy compression. IEEE Trans. Med. Imaging. 24, 743–754 (2005)
S. Paris, F. Durand, A fast approximation of the bilateral filter using a signal processing approach. Int. J. Comput. Vis. 81, 24–52 (2009)
S. Parrilli, M. Poderico, C.V. Angelino, A nonlocal SAR image denoising algorithm based on LLMMSE wavelet shrinkage. IEEE Trans. Geosci. Remote Sens. 50, 606–616 (2012)
C. Pierrick, H. Pierre, K. Charles, Nonlocal means-based speckle filtering for ultrasound images. IEEE Trans. Image Process. 18, 2221–2229 (2009)
S. Poornachandra, Wavelet-based denoising using subband dependent threshold for ECG signals. Digital Signal Process. 18, 49–55 (2008)
A.F. Santiago, A.L. Carlos, On the estimation of the coefficient of variation for anisotropic diffusion speckle filtering. IEEE Trans. Image Process. 15, 2694–2701 (2006)
F. Seán, G. Martin, J. Edward, Echocardiographic speckle reduction comparison. IEEE Trans. Ultrason. Ferroelectr. Freq. Control. 58, 82–101 (2011)
J. Tang, S. Guo, Q. Sun, Speckle reducing bilateral filter for cattle follicle segmentation. BMC Genom. 11, 1471–1480 (2010)
C. Tomasi, R. Manduchi, Bilateral filtering for gray and color images, in The Sixth IEEE International Conference on Computer Vision, pp. 839–846 (1998)
T. Vaudrey, R. Klette, Fast trilateral filtering. Lect. Notes Comput. Sci. 5702, 541–548 (2009)
W. Zhou, B. Alan Conrad, S. Hamid Rahim, Image quality assessment: from error visibility to structural similarity. IEEE Trans. Image Process. 13, 600–612 (2004)
X. Zong, A.F. Laine, E.A. Geiser, Speckle reduction and contrast enhancement of echocardiograms via multiscale nonlinear. IEEE Trans. Med. Imaging. 17, 532–540 (1998)
Acknowledgments
The authors would like to thank the anonymous reviewers for their valuable comments and suggestions that will help improve the manuscript. The authors would also like to thank the people who provide the MATLAB code or executable file, especially Timothy Huegerich for his trilateral filter. The work is partially supported by National Natural Science Foundation of China (60974042) and by Research Project of Zhejiang Province for Public Welfare (2016C33122).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Zhang, J., Wu, L., Lin, G. et al. An Integrated De-speckling Approach for Medical Ultrasound Images Based on Wavelet and Trilateral Filter. Circuits Syst Signal Process 36, 297–314 (2017). https://doi.org/10.1007/s00034-016-0305-8
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00034-016-0305-8