Skip to main content

Advertisement

Log in

Brain MRI tumour classification using quantum classical convolutional neural net architecture

  • Original Article
  • Published:
Neural Computing and Applications Aims and scope Submit manuscript

Abstract

The use of quantum machines leverages the performance of classical machines in many aspects of solving real-world problems. Classification of a brain MR image for detection of tumour regions is a widely performed diagnostic step when it comes to working with brain images. Classical machine learning methods and/or conventional deep learning architectures including convolutional nets are commonly used for the classification of images. With larger network size, training the model becomes a challenging task to undertake. Quantum algorithms are beneficial in optimizing the performance of classical algorithms by incorporating intrinsic properties of quantum bits. In this paper, a novel Quantum Classical ConvNet architecture (QCCNN) is proposed for a binary class classification of brain MR images for detection of tumour regions in the human brain. The underlying idea is to encode data into quantum states enabling a faster extraction of information followed by using the information to distinguish the class of data. The reliability and the robustness of the proposed architecture are highlighted by the results obtained by the classifier. With technological advancements in quantum computers in the future (more qubits and less noise), the performance of the approach can be further improved. The presented model is tested on various datasets (Brats 2013, Harvard Med School, private dataset) and on quantitative evaluation with standard metrics, and the robustness of the classifier is verified. The proposed QCCNN model achieves accuracies in the range of 97.5–98.72% on different datasets which defend the ability of the presented architecture in detecting and classifying brain tumours.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8

Similar content being viewed by others

Explore related subjects

Discover the latest articles, news and stories from top researchers in related subjects.

Data availability statements

The datasets generated during and/or analysed during the current study are available in the Harvard Medical dataset and BRATS 2013 dataset [27] repository. For private datasets, the datasets generated during and/or analysed during the current study are not publicly available but will be available from the corresponding author on reasonable request.

References

  1. Singh L, Chetty G, Sharma D (2012) A novel machine learning approach for detecting the brain abnormalities from mri structural images. In: IAPR international conference on pattern recognition in bioinformatics. Springer, pp 94–105

  2. Das V, Rajan J (2016) Techniques for MRI brain tumor detection: a survey. Int J Res Comput Appl Inf Tech 4(3):53e6

    Google Scholar 

  3. Khambhata KG, Panchal SR (2016) Multiclass classification of brain tumor in MR images. Int J Innov Res Comput Commun Eng 4(5):8982

    Google Scholar 

  4. Abiwinanda N, Hanif M, Hesaputra ST, Handayani A, Mengko TR (2019) Brain tumor classification using convolutional neural network. In: World congress on medical physics and biomedical engineering 2018. Springer, pp 183–189

  5. Kaur G and Rani J (2016) MRI brain tumor segmentation methods-a review. Int J Comput Eng Tech (IJCET) 6(3):760–764

    Google Scholar 

  6. Kavitha A, Chitra L, Kanaga R (2016) Brain tumor segmentation using genetic algorithm with SVM classifier. Int J Adv Res Electr Electron Instrum Eng 5(3):1468

    Google Scholar 

  7. Logeswari T, Karnan M (2010) An improved implementation of brain tumor detection using segmentation based on hierarchical self organizing map. Int J Comput Theory Eng 2(4):591

    Article  Google Scholar 

  8. Konar D, Bhattacharyya S, Panigrahi BK, Behrman EC (2021) Qutrit-inspired fully self-supervised shallow quantum learning network for brain tumor segmentation. IEEE Trans Neural Netw Learn Syst. arXiv:2009.06767

    Article  Google Scholar 

  9. Pereira S, Pinto A, Alves V, Silva CA (2016) Brain tumor segmentation using convolutional neural networks in MRI images. IEEE Trans Med Imaging 35(5):1240

    Article  Google Scholar 

  10. Kaya IE, Pehlivanlı AÇ, Sekizkardeş EG, Ibrikci T (2017) PCA based clustering for brain tumor segmentation of T1w MRI images. Comput Methods Progr Biomed 140:19

    Article  Google Scholar 

  11. Mathew AR, Anto PB (2017) Tumor detection and classification of MRI brain image using wavelet transform and SVM. In: 2017 International conference on signal processing and communication (ICSPC). IEEE, pp 75–78

  12. Litjens G, Kooi T, Bejnordi BE, Setio AAA, Ciompi F, Ghafoorian M, Van Der Laak JA, Van Ginneken B, Sánchez CI (2017) A survey on deep learning in medical image analysis. Med Image Anal 42:60

    Article  Google Scholar 

  13. Gu J, Wang Z, Kuen J, Ma L, Shahroudy A, Shuai B, Liu T, Wang X, Wang G (2015) Recent advances in convolutional neural networks. arXiv:1512.07108

  14. Reza SM, Mays R, Iftekharuddin KM (2015) Multi-fractal detrended texture feature for brain tumor classification. In: Medical imaging 2015: computer-aided diagnosis, vol. 9414. International Society for Optics and Photonics, pp 9414:941410

  15. Gupta T, Manocha P, Gandhi TK, Gupta R, Panigrahi BK (2017) Tumor classification and segmentation of MR brain images. arXiv:1710.11309

  16. Vishnuvarthanan G, Rajasekaran MP, Subbaraj P, Vishnuvarthanan A (2016) An unsupervised learning method with a clustering approach for tumor identification and tissue segmentation in magnetic resonance brain images. Appl Soft Comput 38:190

    Article  Google Scholar 

  17. Khan MA, Lali IU, Rehman A, Ishaq M, Sharif M, Saba T, Zahoor S, Akram T (2019) Brain tumor detection and classification: A framework of marker-based watershed algorithm and multilevel priority features selection. Microsc Res Tech 82(6):909

    Article  Google Scholar 

  18. Islam R, Imran S, Ashikuzzaman M, Khan MMA (2020) Detection and classification of brain tumor based on multilevel segmentation with convolutional neural network. J Biomed Sci Eng 13(4):45

    Article  Google Scholar 

  19. Kumar A, Ramachandran M, Gandomi AH, Patan R, Lukasik S, Soundarapandian RK (2019) A deep neural network based classifier for brain tumor diagnosis. Appl Soft Comput 82:105528

    Article  Google Scholar 

  20. Sharif M, Amin J, Yasmin M, Rehman A (2020) Efficient hybrid approach to segment and classify exudates for DR prediction. Multimedia Tools Appl 79(15):11107

    Article  Google Scholar 

  21. Boixo S, Isakov SV, Smelyanskiy VN, Babbush R, Ding N, Jiang Z, Bremner MJ, Martinis JM, Neven H (2018) Characterizing quantum supremacy in near-term devices. Nat Phys 14(6):595

    Article  Google Scholar 

  22. Arute F, Arya K, Babbush R, Bacon D, Bardin JC, Barends R, Biswas R, Boixo S, Brandao FG, Buell DA et al (2019) Quantum supremacy using a programmable superconducting processor. Nature 574(7779):505

    Article  Google Scholar 

  23. Dunjko V, Briegel HJ (2018) Machine learning and artificial intelligence in the quantum domain: a review of recent progress. Rep Prog Phys 81(7):074001

    Article  Google Scholar 

  24. Biamonte J, Wittek P, Pancotti N, Rebentrost P, Wiebe N, Lloyd S (2017) Quantum machine learning. Nature 549(7671):195

    Article  Google Scholar 

  25. McClean JR, Romero J, Babbush R, Aspuru-Guzik A (2016) The theory of variational hybrid quantum-classical algorithms. New J Phys 18(2):023023

    Article  MATH  Google Scholar 

  26. Konar D, Bhattacharyya S, Gandhi TK, Panigrahi BK, Jiang R (2021) 3D Quantum-inspired self-supervised tensor network for volumetric segmentation of medical images. TechRxiv Prepr https://doi.org/10.36227/techrxiv.12909860

    Article  Google Scholar 

  27. Menze BH, Jakab A, Bauer S, Kalpathy-Cramer J, Farahani K, Kirby J, Burren Y, Porz N, Slotboom J, Wiest R et al (2014) The multimodal brain tumor image segmentation benchmark (BRATS). IEEE Trans Med Imaging 34(10):1993

    Article  Google Scholar 

  28. Summers D (2003) Harvard whole brain atlas. J Neurol Neurosurg Psychiatry 74(3):288

    Article  Google Scholar 

  29. Dunjko V, Taylor JM, Briegel HJ (2016) Quantum-enhanced machine learning. Phys Rev Lett 117(13):130501

    Article  Google Scholar 

  30. Aïmeur E, Brassard G, Gambs S (2006) Machine learning in a quantum world. In: Conference of the Canadian society for computational studies of intelligence. Springer, pp 431–442

  31. Ortiz G, Gubernatis JE, Knill E, Laflamme R (2001) Quantum algorithms for fermionic simulations. Phys Rev A 64(2):022319

    Article  Google Scholar 

  32. Taube AG, Bartlett RJ (2006) New perspectives on unitary coupled-cluster theory. Int J Quantum Chem 106(15):3393

    Article  Google Scholar 

  33. Bergholm V, Izaac J, Schuld M, Gogolin C, Alam MS, Ahmed S, Arrazola JM, Blank C, Delgado A, Jahangiri S, et al. (2018) Pennylane: automatic differentiation of hybrid quantum-classical computations. arXiv:1811.04968

  34. Henderson M, Shakya S, Pradhan S, Cook T (2020) Quanvolutional neural networks: powering image recognition with quantum circuits. Quantum Mach Intell 2(1):1

    Article  Google Scholar 

  35. Abohashima Z, Elhosen M, Houssein EH, Mohamed WM (2020) Classification with quantum machine learning: a survey. arXiv:2006.12270

  36. Broughton M, Verdon G, McCourt T, Martinez AJ, Yoo JH, Isakov SV, Massey P, Niu MY, Halavati R, Peters E, et al (2020) Tensorflow quantum: a software framework for quantum machine learning. arXiv:2003.02989

  37. Campbell SL, Gear CW (1995) The index of general nonlinear DAES. Numer Math 72(2):173

    Article  MATH  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Amiya Halder.

Ethics declarations

Conflict of interest

The authors declare no conflict of interest.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Choudhuri, R., Halder, A. Brain MRI tumour classification using quantum classical convolutional neural net architecture. Neural Comput & Applic 35, 4467–4478 (2023). https://doi.org/10.1007/s00521-022-07939-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00521-022-07939-2

Keywords