Abstract
Heart rate variability (HRV) is an indicator of changes in the interval between successive R-waves on the electrocardiogram (ECG), known as R–R intervals (RRI), caused by autonomic nervous system activity. Measurement of RRI is useful in detecting diseases related to autonomic nervous system activity and predicting seizures. This study proposes an improved heart-rate measurement system that combines a highly accurate, compact, and inexpensive patch-type RRI telemeter with a smartphone application that automatically selects the appropriate measurement position without the need of an expert. To evaluate the measurement accuracy, the RRIs of 10 healthy men and 10 healthy women in supine, sitting, standing, and walking (3 km/h) postures were simultaneously measured using the proposed system and a reference ECG measurement system, and the obtained results were compared. Furthermore, the R-wave detection rate was measured, and Bland–Altman analysis was conducted to analyze the measurement accuracy of the proposed system. The results show that the R-wave detection rate and limit-of-agreement were sufficiently accurate for HRV analysis for 68 and 67 out of the total of 80 epochs, respectively. The fabricated system is expected to enhance the ability of non-experts to conduct ECG measurements and will contribute to improve the quality of healthcare through continuous monitoring at home.











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Acknowledgements
This work was supported in part by JSPS KAKENHI Grant Number 21H03855 and by the research project for medical engineering collaboration and implementation of artificial intelligence from the Japanese Agency for Medical Research and Development (AMED) Grant Number 21445838.
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This work was presented in part at the joint symposium of the 27th International Symposium on Artificial Life and Robotics, the 7th International Symposium on BioComplexity, and the 5th International Symposium on Swarm Behavior and Bio-Inspired Robotics (Online, January 25-27, 2022).
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Noguchi, A., Takano, T., Fujiwara, K. et al. Interactive system for optimal position selection of a patch-type R–R interval telemeter. Artif Life Robotics 28, 226–235 (2023). https://doi.org/10.1007/s10015-022-00815-1
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DOI: https://doi.org/10.1007/s10015-022-00815-1