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Human–simian correspondence in the early cortical processing of multisensory cues

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Abstract

Recent findings in both monkeys and humans indicate that multisensory convergence occurs in low-level cortical structures generally believed to be unisensory in function. There is also evidence that multisensory convergence in higher-order regions occurs at very short post-stimulus latencies. Both types of convergence are of interest as they represent substrates for multisensory interactions in early cortical processing. This paper reviews the correspondence between specific findings in humans and monkeys, focusing on two areas, posterior auditory association cortex and posterior parietal visual association cortex. In each case we examine evidence for “low-level” and/or “early” multisensory convergence in humans, and then examine the results of direct physiological investigation of homologous effects in macaque monkeys. The latter allow a precise physiological and anatomical description of the effects noted in human subjects to be found. We then consider the functional implications of multisensory integration in early and low-level sensory processing, both in relation to our basic hierarchical model of cortical processing and in relation to our understanding of multisensory processes in perception. We end by considering the importance of human–simian homology in the study of the multisensory components of primate (human and monkey) communication.

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Notes

  1. The actual electrophysiological recording procedure is to record sensory-evoked field potentials and action potentials from each of the contacts of the multielectrode, and CSD is then calculated using a second-derivative approximation applied to the field potential profile (Nicholson 1973).

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Acknowledgements

Thanks to Micah Murray and Ankoor Shah for helpful discussions, and to T. McGinnis and Noelle O’Connell for excellent technical and conceptual assistance. This work was supported in part by grants from the National Institute of Mental Health MH61989 and TW05674.

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Authors and Affiliations

  1. Cognitive Neuroscience and Schizophrenia Program, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Rd., Bldg. 37, Orangeburg, NY, 10962, USA

    Charles E. Schroeder, Sophie Molhom, Peter Lakatos, Walter Ritter & John J. Foxe

  2. Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY, USA

    Charles E. Schroeder & John J. Foxe

  3. Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA

    Charles E. Schroeder

  4. Department of Psychiatry, Albert Einstein College of Medicine, Bronx, NY, USA

    John J. Foxe

  5. Institute for Psychology, Hungarian Academy of Sciences, Budapest, Hungary

    Peter Lakatos

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  1. Charles E. Schroeder
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  2. Sophie Molhom
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  4. Walter Ritter
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  5. John J. Foxe
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Correspondence to Charles E. Schroeder.

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Edited by: Marie-Hélène Giard and Mark Wallace

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Schroeder, C.E., Molhom, S., Lakatos, P. et al. Human–simian correspondence in the early cortical processing of multisensory cues. Cogn Process 5, 140–151 (2004). https://doi.org/10.1007/s10339-004-0020-4

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