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ADAAPT: Amgen's data access, analysis, and prediction tools

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The Amgenȁ9s Data Access Analysis Prediction Tools (ADAAPT) system is a desktop decision support tool developed to provide flexible access and analysis of chemical and biological data. The system is platform independent, adaptable, easily deployed, and scalable. It consists of four main modules: access, analysis, prediction, and tools. The access module contains numerous user interfaces designed to retrieve data easily. The analysis module provides standard computational tools to perform property calculation, QSAR/QSPR, and statistical analyses. The prediction module contains in-house models to calculate a drug-likeness score and absorption index. Finally, the tools module provides a wide array of features that are of general interest to our scientists.

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Acknowledgement

We are grateful for helpful discussions and feedback from other members of the modeling group at Amgen. We especially thank Michael Bartberger, Matthew Lee, and Mick Kappler for their critical reading of the manuscript.

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Authors and Affiliations

  1. Molecular Structure, Amgen Inc., MS 29-M-B, One Amgen Center Drive, Thousand Oaks, CA, 91320, USA

    Sung Jin Cho, Yaxiong Sun & William Harte

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  1. Sung Jin Cho
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  2. Yaxiong Sun
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  3. William Harte
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Correspondence to Sung Jin Cho.

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Cho, S.J., Sun, Y. & Harte, W. ADAAPT: Amgen's data access, analysis, and prediction tools. J Comput Aided Mol Des 20, 249–261 (2006). https://doi.org/10.1007/s10822-006-9048-0

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  • DOI: https://doi.org/10.1007/s10822-006-9048-0

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