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The effects of tautomerism on the nature of molecules in the solid state

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Abstract

Tautomerism is a phenomenon well know to most chemists but frequently forgotten when chemistry leaves the bench and enters the computational realm. Through the examination of several examples from the crystallographic literature it can be clearly demonstrated that the tautomeric state of a molecules can strongly affect its nature.

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Authors and Affiliations

  1. Structural Chemistry, Global Pharmaceutical R & D, Abbott Laboratories, 100 Abbott Park Rd., Abbott Park, IL, 60064, USA

    Rodger F. Henry

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  1. Rodger F. Henry
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Correspondence to Rodger F. Henry.

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Henry, R.F. The effects of tautomerism on the nature of molecules in the solid state. J Comput Aided Mol Des 24, 587–590 (2010). https://doi.org/10.1007/s10822-010-9351-7

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  • DOI: https://doi.org/10.1007/s10822-010-9351-7

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