Abstract
In this study, an E-Nose system was realized for the anesthetic dose level prediction. For this purpose, sevoflurane anesthetic agent was measured using the E-Nose system implemented with sensor array of quartz crystal microbalances (QCM). In surgeries, anesthetic agents are given to the patients with carrier gases of oxygen (O2) and nitrous oxide (N2O). Frequency changes on QCM sensors to the eight sevoflurane anesthetic dose levels were recorded via RS-232 serial port. A multilayer feed forward artificial neural network (MLNN) structure was used to provide the relationship between the frequency change and the anesthetic dose level. The MLNNs were trained with the measured data using Levenberg–Marquardt algorithm. Then, the trained MLNNs were tested with random data. The results have showed that, acceptable anesthetic dose level predictions have been obtained successfully.
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Acknowledgments
The work supported by TUBITAK under project # 104E053: “Diagnosing System Design for Medical Applications Using by QCM-SSC Gas Sensor Array” and Scientific Search Project of Dumlupınar University, 2004-6: “Real Time Detection of the Anesthetic Gases by Using PC(PIC) & QCM Sensor Array”. The sensors used in this study were manufactured by TUBITAK MAM Sensor Technologies Laboratory researches. We would like to thank them for their kind support.
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Saraoğlu, H.M., Edin, B. E-Nose System for Anesthetic Dose Level Detection using Artificial Neural Network. J Med Syst 31, 475–482 (2007). https://doi.org/10.1007/s10916-007-9087-7
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DOI: https://doi.org/10.1007/s10916-007-9087-7