Abstract
Chronic Obstructive Pulmonary Disease (COPD) is a disease state characterized by airflow limitation that is not fully reversible. The airflow limitation is usually both progressive and associated with an abnormal inflammatory response of the lungs to noxious particles or gases. COPD is important health problem and one of the most common illnesses in Turkey. It is generally accepted that cigarette smoking is the most important risk factor and genetic factors are believed to play a role in the individual susceptibility. In this study, a study on COPD diagnosis was realized by using multilayer neural networks (MLNN). For this purpose, two different MLNN structures were used. One of the structures was the MLNN with one hidden layer and the other was the MLNN with two hidden layers. Back propagation with momentum and Levenberg–Marquardt algorithms were used for the training of the neural networks. The COPD dataset were prepared from a chest diseases hospital’s database using patient’s epicrisis reports.

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Molfino, N. A., and Jeffery, P. K., Chronic obstructive pulmonary disease: Histopathology, inflammation and potential therapies. Pulm. Pharmacol. Ther. 20:5462–472, 2007.
Molfino, N. A., Drugs in clinical development for chronic obstructive pulmonary disease. Respiration. 72:1105–112, 2005.
Jeffery, P. K., Structural and inflammatory changes in COPD: A comparison with asthma. Thorax. 53:2129–136, 1998.
Sönmez, S., and Uzaslan, E., Kronik Obstrüktif Akciğer Hastalığı’nın Genetiği ve Sitokin Gen Polimorfizmi - Derleme. Archives of Lung, Cilt. 7:75–78, 2006.
Samurkaşoğlu, B., Epidemiyoloji ve risk faktörleri. In: Saryal, S. B., and Acican, T. (Eds.), Güncel Bilgiler Işığında KOAHBilimsel Tıp Yayınevi. Sayfa, Ankara, pp. 9–19, 2003.
Pocket Guide To COPD Diagnosis, Management, And Prevention, National Heart, Lung, And Blood Institute, 2003.
Rumelhart, D. E., Hinton, G. E., and Williams, R. J., Learning internal representations by error propagation. In: Rumelhart, D. E., and McClelland, J. L. (Eds.), Parallel Distributed Processing: Explorations in the Microstructure of Cognition, Vol. 1MIT Press, Cambridge, MA, USA, pp. 318–362, 1986.
Brent, R. P., Fast training algorithms for multi-layer neural nets. IEEE Trans. Neural. Netw. 2:346–354, 1991.
Gori, M., and Tesi, A., On the problem of local minima in backpropagation. IEEE Trans. Pattern Anal. Machine Intell. 14:76–85, 1992.
Hagan, M. T., and Menhaj, M., Training feed forward networks with the Marquardt algorithm. IEEE Trans. Neural Netw. 5:989–993, 1994.
Hagan, M. T., Demuth, H. B., and Beale, M. H., Neural network design. PWS Publishing, Boston, MA, USA, 1996.
Sagiroglu, S., Besdok, E., and Erler, M., Control chart pattern recognition using artificial neural networks. Turk. J. Elec. Engin. 8:137–146, 2000.
Gulbag, A., and Temurtas, F., A study on quantitative classification of binary gas mixture using neural networks and adaptive neuro fuzzy inference systems. Sens. Actuators B. 115:252–262, 2006.
Matlab® Documentation, Version 7.0, Release 14, The MathWorks, Inc.
Ashizawa, K., Ishida, T., MacMahon, H., Vyborny, C. J., Katsuragawa, S., Doi, K., and Rossman, K., Artificial neural networks in chest radiography: Application to the differential diagnosis of interstitial lung disease. Acad. Radiol. 11:129–37, 2005.
Coppini, G., Miniati, M., Paterni, M., Monti, S., and Ferdeghini, E. M., Computer-aided diagnosis of emphysema in COPD patients:Neural-network-based analysis of lung shape in digital chest radiographs. Med. Eng. Phys. 29:76–86, 2007.
Watkins, A. AIRS: A resource limited artificial immune classifier. Master Thesis, Mississippi State University, 2001.
Temurtas, F., A comparative study on thyroid disease diagnosis using neural networks. Expert Systems With Applications, in press, DOI 10.1016/j.eswa.2007.10.010, 2007.
Delen, D., Walker, G., and Kadam, A., Predicting breast cancer survivability: A comparison of three data mining methods. Artif. Intell. Med. 34:2113–127, 2005.
Ozyılmaz, L., Yıldırım, T., Diagnosis of thyroid disease using artificial neural network methods. In Proc. of ICONIP’02 9th international conference on neural information processing. Orchid Country Club, Singapore, pp. 2033–2036, 2002.
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Er, O., Temurtas, F. A Study on Chronic Obstructive Pulmonary Disease Diagnosis Using Multilayer Neural Networks. J Med Syst 32, 429–432 (2008). https://doi.org/10.1007/s10916-008-9148-6
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DOI: https://doi.org/10.1007/s10916-008-9148-6