Skip to main content

Advertisement

Log in

Computerized Disease Profiling Using GPS-Linked Multi-Function Sensor Cartridges

  • Original Paper
  • Published:
Journal of Medical Systems Aims and scope Submit manuscript

Abstract

Disease identification in public health monitoring routinely employs analyte detection systems capable of discriminating mixtures of analytes, toxins, cells and/or bacteria in medical and/or environmental solutions. The development of smart sensors capable of discriminating such compounds has become increasingly important for clinical, environmental, and health applications. While some sensors have been fashioned for single analyte detection, methods and systems that facilitate rapid screening of multiple clinical components are needed, serving as triggers for potential epidemics or more specific confirmatory testing. In public health applications, there is like need for immediate collection of geocoded data tagged by disease identification characteristics, with corresponding alerting capabilities. In this technology review we propose one promising model for using a combination of emerging systems-based technologies in multi sensor cartridges, integrated with GPS-enabled, alert-capable mobile phone devices.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8

Similar content being viewed by others

References

  1. McDevitt, J., Systems and methods including self-contained cartridges with detection systems and fluid delivery systems. United States Patent Application, 20100291588, November 18, 2010.

    Google Scholar 

  2. Banerjee, P., and Bhunia, A. K., Cell-based biosensor for rapid screening of pathogens and toxins. Biosens. Bioelectron. 26(1):99–106, 2010. Epub 2010 May 19.

    Article  Google Scholar 

  3. Garber, E. A., Venkateswaran, K. V., and O’Brien, T. W., Simultaneous multiplex detection and confirmation of the proteinaceous toxins abrin, ricin, botulinum toxins, and Staphylococcus enterotoxins a, B, and C in food. J. Agric. Food Chem. 58(11):6600–6607, 2010.

    Article  Google Scholar 

  4. Yang, M., Sun, S., Bruck, H. A., Kostov, Y., and Rasooly, A., Electrical percolation-based biosensor for real-time direct detection of staphylococcal enterotoxin B (SEB). Biosens. Bioelectron. 25(12):2573–2578, 2010. Epub 2010 Apr 21.

    Article  Google Scholar 

  5. Thomas, A., Schänzer, W., Delahaut, P., and Thevis, M., Sensitive and fast identification of urinary human, synthetic and animal insulin by means of nano-UPLC coupled with high-resolution/high-accuracy mass spectrometry. Drug Test. Anal. 1(5):219–227, 2009.

    Article  Google Scholar 

  6. Burton, R. E., White, E. J., Foss, T. R., Phillips, K. M., Meltzer, R. H., Kojanian, N., Kwok, L. W., Lim, A., Pellerin, N. L., Mamaeva, N. V., and Gilmanshin, R., A microfluidic chip-compatible bioassay based on single-molecule detection with high sensitivity and multiplexing. Lab Chip 10(7):843–851, 2010. Epub 2010 Jan 14.

    Article  Google Scholar 

  7. Chen, H., Hu, Q. Y., Yue-Zheng, Jiang, J. H., Shen, G. L., and Yu, R. Q., Construction of supported lipid membrane modified piezoelectric biosensor for sensitive assay of cholera toxin based on surface-agglutination of ganglioside-bearing liposomes. Anal. Chim. Acta 657(2):204–209, 2010.

    Article  Google Scholar 

  8. Diana Di Mavungu, J., Monbaliu, S., Scippo, M. L., Maghuin-Rogister, G., Schneider, Y. J., Larondelle, Y., Callebaut, A., Robbens, J., Van Peteghem, C., and De Saeger, S., LC-MS/MS multi-analyte method for mycotoxin determination in food supplements. Food Addit. Contam. A Chem. Anal. Control Expo. Risk Assess. 26(6):885–895, 2009.

    Google Scholar 

  9. Gheorghiu, M., Olaru, A., Tar, A., Polonschii, C., and Gheorghiu, E., Sensing based on assessment of non-monotonous effect determined by target analyte: Case study on pore-forming compounds. Biosens. Bioelectron. 24(12):3517–3523, 2009. Epub 2009 May 14.

    Article  Google Scholar 

  10. Dover, J. E., Hwang, G. M., Mullen, E. H., Prorok, B. C., and Suh, S. J., Recent advances in peptide probe-based biosensors for detection of infectious agents. J. Microbiol. Methods 78(1):10–19, 2009. Epub 2009 Apr 24. Review.

    Article  Google Scholar 

  11. McDevitt, J., Systems and methods including self-contained cartridges with detection systems and fluid delivery systems. United States Patent Application, 20100291588, November 18, 2010.

    Google Scholar 

  12. King, R., Portable pulse monitoring device and method of its operation. United States Patent Application, 20060152373, July 13, 2006.

    Google Scholar 

  13. McDevitt, J., Systems and methods including self-contained cartridges with detection systems and fluid delivery systems. United States Patent Application, 20100291588, November 18, 2010.

    Google Scholar 

  14. King, R., Portable pulse monitoring device and method of its operation. United States Patent Application, 20060152373, July 13, 2006.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Daniel Lorence.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lorence, D., Wu, J. Computerized Disease Profiling Using GPS-Linked Multi-Function Sensor Cartridges. J Med Syst 36, 2537–2545 (2012). https://doi.org/10.1007/s10916-011-9726-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10916-011-9726-x

Keywords

Navigation